1474060-74-6

Upstream product

• 91-23-6 2-Nitroanisole 
• 24424-99-5 di-tert-butyl dicarbonate 
• 77770-09-3 3-amino-4-methyloxyphenyliodide 
• 52692-09-8 4-iodo-2-nitroanisole 

Downstream Products

• 1474060-73-5 1-[3'-(N-tert-butyloxycarbonylamino)-4'-methoxyphenyl]-1-(3'',4'',5''-trimethoxyphenyl)ethylene 
• 1204138-92-0 tert-butyl (2-methoxy-5-((3,4,5-trimethoxyphenyl)ethynyl)phenyl)carbamate 
• 262433-23-8 2-(3-tert-butoxycarbonylamino-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1560773-80-9 (S)-4-[3-(2-amino-3-hydroxypropanoylamino)-4-methoxyphenyl]-5,6,7-trimethoxycoumarin hydrochloride 
• 1560773-79-6 (S)-4-[3-(2-amino-3-hydroxypropanoylamino)-4-methoxyphenyl]-5,7-dimethoxycoumarin hydrochloride 
• 1560773-76-3 (S)-4-[3-(2-amino-3-hydroxypropanoylamino)-4-methoxyphenyl]-6-methoxycoumarin hydrochloride 
• 1560773-72-9 (S)-4-[3-(2-amino-3-hydroxypropanoylamino)-4-methoxyphenyl]-5-methoxycoumarin hydrochloride 
• 1560773-71-8 (S)-4-[3-(2-amino-3-hydroxypropanoylamino)-4-methoxyphenyl]coumarin hydrochloride 
• 1560773-69-4 (S)-4-{3-[3-benzyloxy-2-(tert-butoxycarbonylamino)propanoylamino]-4-methoxyphenyl}-5,6,7-trimethoxycoumarin 
• 1560773-66-1 (S)-4-{3-[3-benzyloxy-2-(tert-butoxycarbonylamino)propanoylamino]-4-methoxyphenyl}-5,7-dimethoxycoumarin 
• 1560773-64-9 (S)-4-{3-[3-benzyloxy-2-(tert-butoxycarbonylamino)propanoylamino]-4-methoxyphenyl}-6-methoxycoumarin 
• 1560773-61-6 (S)-4-{3-[3-benzyloxy-2-(tert-butoxycarbonylamino)propanoylamino]-4-methoxyphenyl}-5-methoxycoumarin 
• 1560773-59-2 (S)-4-{3-[3-benzyloxy-2-(tert-butoxycarbonylamino)propanoylamino]-4-methoxyphenyl}coumarin 
• 1560773-57-0 4-(3-amino-4-methoxyphenyl)-5,6,7-trimethoxycoumarin 

Relevant academic research and scientific papers

Novel water-soluble anticancer agents derived from 4-arylcoumarins

Novel 4-arylcoumarin derivatives were obtained. They are water-soluble analogs of the well-known anticancer drug combretastatin A-4. The key step of the synthesis involves the Suzuki-Miyaura cross-coupling. The water-soluble salts obtained exhibit conside

Negishi cross-coupling reaction as a route to isocombretastatins

A series of isocombretastatins A has been synthesized by a new method based on the Negishi cross-coupling reaction in 19-84% yields. Five of the synthesized compounds exhibit high cytotoxic activity in nanomolar concentrations (IC50 = 1-100 n) towards Jurkat, K562, Colo357, and A549 cell lines. Georg Thieme Verlag Stuttgart · New York.