147410-41-1Relevant academic research and scientific papers
Effects of remote N-(tert-butoxycarbonyl) groups on heteroatom directed lithiation at benzylic positions
Clark, Robin D.,Jahangir
, p. 1351 - 1356 (1993)
Lithiation of N-BOC-2-methylphenethylamine (6) occurs exclusively at the methyl group whereas lithiation of the phenylpropyl congener (11) is less regioselective. N-BOC-phenylpropylamine (17) is efficiently lithiated at the benzylic position while N-BOC-2
Stereoselective synthesis of trans-2,3-disubstituted pyrrolidines via addition to N-acyliminium ions
Buezo, Nuria Diaz,Jiménez, Alma,Pedregal, Concepción,Vidal, Paloma
, p. 2489 - 2492 (2007/10/03)
An efficient and stereoselective synthesis of trans-2,3-disubstituted pyrrolidines is described. The intermolecular alkylation of racemic N-acyliminium ions generated in situ from the corresponding 3-substituted lactams proceeds stereoselectively and in h
