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147410-43-3

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147410-43-3 Usage

General Description

1-Boc-3-phenyl-pyrrolidine is a chemical compound with the molecular formula C16H23NO2. It is a derivative of pyrrolidine and contains a tert-butoxycarbonyl (Boc) protecting group and a phenyl group attached to the nitrogen atom. 1-Boc-3-phenyl-pyrrolidine is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It has also been studied for its potential use in the development of new drugs. 1-Boc-3-phenyl-pyrrolidine is a white to off-white solid, and its properties and reactivity make it useful in various organic synthesis applications.

Check Digit Verification of cas no

The CAS Registry Mumber 147410-43-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,4,1 and 0 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 147410-43:
(8*1)+(7*4)+(6*7)+(5*4)+(4*1)+(3*0)+(2*4)+(1*3)=113
113 % 10 = 3
So 147410-43-3 is a valid CAS Registry Number.
InChI:InChI=1/C15H21NO2/c1-15(2,3)18-14(17)16-10-9-13(11-16)12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3

147410-43-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-Butyl 3-phenylpyrrolidine-1-carboxylate

1.2 Other means of identification

Product number -
Other names 1-tert-butoxycarbonyl-3-phenyl-pyrrolidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:147410-43-3 SDS

147410-43-3Downstream Products

147410-43-3Relevant articles and documents

A new synthesis of 3-substituted pyrrolidines using iron catalysed cross-coupling reactions and ring closing metathesis

?stergaard, Niels,Thoning Pedersen, Brian,Skj?rb?k, Niels,Veds?, Per,Begtrup, Mikael

, p. 1889 - 1891 (2002)

A series of 3-substituted N-Boc protected pyrrolidines have been prepared via iron catalysed cross-coupling between Boc protected N-allyl-N-(2-bromoallyl)amine 3 and organomagnesium compounds followed by ring closing metathesis and subsequent hydrogenatio

Cobalt-Catalyzed C(sp2)-C(sp3) Suzuki-Miyaura Cross Coupling

Ludwig, Jacob R.,Simmons, Eric M.,Wisniewski, Steven R.,Chirik, Paul J.

, (2020/11/02)

A cobalt-catalyzed method for the C(sp2)-C(sp3) Suzuki-Miyaura cross coupling of aryl boronic esters and alkyl bromides is described. Cobalt-ligand combinations were assayed with high-throughput experimentation, and cobalt(II) sources with trans-N,N′-dimethylcyclohexane-1,2-diamine (DMCyDA, L1) produced optimal yield and selectivity. The scope of this transformation encompassed steric and electronic diversity on the aryl boronate nucleophile as well as various levels of branching and synthetically valuable functionality on the electrophile. Radical trap experiments support the formation of electrophile-derived radicals during catalysis.

Iron- and cobalt-catalyzed arylation of azetidines, pyrrolidines, and piperidines with grignard reagents

Barr, Baptiste,Gonnard, Laurine,Campagne, Rmy,Reymond, Sbastien,Marin, Julien,Ciapetti, Paola,Brellier, Marie,Gurinot, Amandine,Cossy, Janine

supporting information, p. 6160 - 6163 (2015/01/16)

Iron- and cobalt-catalyzed cross-couplings between iodo-azetidines, -pyrrolidines, -piperidines, and Grignard reagents are disclosed. The reaction is efficient, cheap, chemoselective and tolerates a large variety of (hetero)aryl Grignard reagents.

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