14755-55-6

Basic information

• Product Name: Ethanone, 2-chloro-2-(methylthio)-1-phenyl-
• CAS NO: 14755-55-6
• Molecular Formula: C9H9ClOS
• Molecular Weight: 200.689
• Mol File: 14755-55-6.mol

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-chloro-2-(methylthio)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-chloro-2-(methylthio)-1-phenyl-(14755-55-6)
• EPA Substance Registry System: Ethanone, 2-chloro-2-(methylthio)-1-phenyl-(14755-55-6)

Safety Data

• Hazardous Substances Data: 14755-55-6(Hazardous Substances Data)

Upstream product

• 2813-22-1 2-methanesulfinyl-1-phenyl-ethanone 
• 5398-93-6 2-methylthio-1-phenyl-ethanone 

Downstream Products

• 97781-07-2 2-Benzo[1,3]dioxol-5-yl-2-methylsulfanyl-1-phenyl-ethanone 
• 98910-27-1 2-(1-Methylsulfanyl-2-oxo-2-phenyl-ethyl)-cyclohexanone 
• 13865-06-0 α-(methylthio)benzyl methyl ether 
• 82834-06-8 Methoxy-methylsulfanyl-phenyl-acetaldehyde 
• 344306-19-0 2-(1-Methylsulfanyl-2-oxo-2-phenyl-ethyl)-cyclopentanone 
• 86998-17-6 2-[2-Oxo-2-phenyl-eth-(E)-ylidene]-cyclohexanone 
• 33553-23-0 2-phenacylcyclohexanone 
• 134-81-6 benzil 
• 86358-27-2 1-(benzo[d][1,3]dioxol-5-yl)-2-phenylethane-1,2-dione 
• 79997-18-5 1-(3,4-dimethoxyphenyl)-2-phenylethane-1,2-dione 
• 151026-97-0 diethyl 1-methylthio-2-oxo-2-phenylethylphosphonate 
• 32368-19-7 1,2-diphenyl-2-methylthio-1-ethanone 
• 94741-88-5 7-(methylthio)bicyclo<4.1.0>hept-2-en-7-yl phenyl ketone 
• 344338-63-2 2-Methyl-2-(1-methylsulfanyl-2-oxo-2-phenyl-ethyl)-cyclohexanone 

Relevant articles and documents

α-Alkyl(aryl)sulfenyl substituted β-ketophosphonates: Synthesis, properties and reactivity

A new synthesis of the title compounds via acylation of α-lithio-α-phosphorylalkyl sulfides is described. Two additional approaches to these compounds, although less efficient, involve: (a) sulfenylation of O-silylated dialkyl β-ketophosphonates and (b) the Arbuzov reaction of triethyl phosphite with α-chloro-α- methylthiomethyl phenyl ketone. The keto-enol tautomerism of the title compounds and reactivity of the anions derived from them with electrophilic reagents were investigated. The P(O)-olefination products obtained from electron rich aromatic aldehydes were found to undergo the acid-catalyzed desulfenylation reaction affording α,β-unsaturated ketones.

Synthesis of unsymmetrically substituted benzils via the Friedel-Crafts reaction of arenes with α-chloro-α-(methylthio)acetophenones

Lewis acid-promoted reactions of arenes with α-chloro-α-(methylthio)acetophenones gave the Friedel-Crafts reaction products, which were then treated with 3 molar eq of cupric chloride in aqueous acetone to afford the unsymmetrically substituted benzils.