97781-07-2

Basic information

• Product Name: 2-Benzo[1,3]dioxol-5-yl-2-methylsulfanyl-1-phenyl-ethanone
• Synonyms: 2-Benzo[1,3]dioxol-5-yl-2-methylsulfanyl-1-phenyl-ethanone
• CAS NO: 97781-07-2
• Molecular Weight: 286.351
• Mol File: 97781-07-2.mol

Chemical Properties

• CAS DataBase Reference: 2-Benzo[1,3]dioxol-5-yl-2-methylsulfanyl-1-phenyl-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzo[1,3]dioxol-5-yl-2-methylsulfanyl-1-phenyl-ethanone(97781-07-2)
• EPA Substance Registry System: 2-Benzo[1,3]dioxol-5-yl-2-methylsulfanyl-1-phenyl-ethanone(97781-07-2)

Safety Data

• Hazardous Substances Data: 97781-07-2(Hazardous Substances Data)

Upstream product

• 274-09-9 Methylenedioxybenzene 
• 14755-55-6 α-benzoyl-α-(methylthio)methyl chloride 
• 2813-22-1 2-methanesulfinyl-1-phenyl-ethanone 
• 5398-93-6 2-methylthio-1-phenyl-ethanone 

Downstream Products

• 86358-27-2 1-(benzo[d][1,3]dioxol-5-yl)-2-phenylethane-1,2-dione 

Relevant articles and documents

Synthesis of unsymmetrically substituted benzils via the Friedel-Crafts reaction of arenes with α-chloro-α-(methylthio)acetophenones

Lewis acid-promoted reactions of arenes with α-chloro-α-(methylthio)acetophenones gave the Friedel-Crafts reaction products, which were then treated with 3 molar eq of cupric chloride in aqueous acetone to afford the unsymmetrically substituted benzils.

MILD REACTION OF PUMMERER REARRANGEMENT PRODUCTS WITH AROMATIC COMPOUNDS IN THE PRESENCE OF LEWIS ACIDS. APPLICATION TO THE PREPARATION OF ARYLMETHYLENE KETONES, ARYLACETOESTERS, AND ARYLACETONITRILES.

Pummerer intermediates generated from precursors (3), (4) and (5) reacted mildly with aromatic compounds in the presence of Lewis acids to give the corresponding sulfides which in turn desulfurized to arylmethylene ketones, arylacetoesters, and arylaceton