147556-43-2Relevant articles and documents
Preparation and x-ray crystal structure of (2Z,4E)-5-(4-substituted phenyl)-3-hydroxy-1-phenylpenta-2,4-dien-1-ones (Curcumin Analogs) from the condensation-elimination of dilithiated 1-benzoylacetone with substituted benzaldehydes
Thomas, Alton R.,Shuler, William G.,Smith, Ellyn A.,Carlisle, Sarah S.,Knick, Shabree L.,Puciaty, Andrew J.,Metz, Clyde R.,Vanderveer, Donald G.,McMillen, Colin D.,Pennington, William T.,Beam, Charles F.
, p. 629 - 635 (2013)
1-Benzoylacetone 1 was dilithiated with lithium diisopropylamide or lithium hexamethyl-disilazide, and the resulting dianion type intermediate 1a was condensed with (lithium) 4-hydroxybenzaldehyde, 4-dimethylaminobenzaldehyde, or 4-chlorobenzaldehyde to a
Synthesis and 1H-NMR Spectroscopic Investigations of New Curcumin Analoga
Arrieta, A.,Beyer, L.,Kleinpeter, E.,Lehmann, J.,Dargatz, M.
, p. 696 - 700 (2007/10/02)
The synthesis of numerous symmetric and non-symmetric curcumin(hetero) analoga (1-3) systematic variation of the conjugated chain and substituents is described.The structure of most compounds is confirmed by 1H-n.m.r.-spectroscopy.All compounds show E-con