14756-21-9Relevant academic research and scientific papers
Fungal metabolism of naphthoflavones
Pop?oński, Jaros?aw,Sordon, Sandra,Tronina, Tomasz,Bartmańska, Agnieszka,Huszcza, Ewa
, p. 1 - 6 (2015/05/05)
Naphthoflavones (benzoflavones) are synthetic flavonoids commonly used in drug metabolism studies as selective activators or inhibitors of cytochrome P-450 enzymes. Nowadays they are also used as a component of food supplements for body builders. There is
Synthesis of methoxybenzoflavones and assignments of their NMR data
Hwang, Doseok,Jo, Geunhyeong,Hyun, Jiye,Lee, Sung Dae,Koh, Dongsoo,Lim, Yoongho
experimental part, p. 62 - 67 (2012/08/08)
A phytotoxic root exudate from Acroptilon repens was identified as 7,8-benzoflavone, an inhibitor of cytochrome P450 1A2 and activator of cytochrome P450 3A4. The synthetic 5,6-benzoflavone also is a potent phytotoxin. Six 7,8-benzoflavones and eight 5,6-benzoflavones were synthesized in this study. The NMR data for a few of these compounds have been previously reported; however, the NMR data for most of them have not been reported. For reference purposes, the complete NMR data for the 14 benzoflavones are described.
