147568-55-6

Basic information

• Product Name: Naphtho[2,3-b]furan-4,9-dione, 2-acetyl-2,3-dihydro-
• CAS NO: 147568-55-6
• Molecular Formula: C14H10O4
• Molecular Weight: 242.231
• Mol File: 147568-55-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Naphtho[2,3-b]furan-4,9-dione, 2-acetyl-2,3-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: Naphtho[2,3-b]furan-4,9-dione, 2-acetyl-2,3-dihydro-(147568-55-6)
• EPA Substance Registry System: Naphtho[2,3-b]furan-4,9-dione, 2-acetyl-2,3-dihydro-(147568-55-6)

Safety Data

• Hazardous Substances Data: 147568-55-6(Hazardous Substances Data)

Upstream product

• 83-72-7 2-hydroxynaphtho-1,4-quinone 
• 61203-01-8 3-bromobut-3-en-2-one 
• 25109-57-3 3,4-dibromobutan-2-one 

Downstream Products

• 83280-65-3 2-acetylnaphtho[2,3-b]furan-4,9-quinone 
• 83889-95-6 2-(1-hydroxy-ethyl)-naphtho[2,3-b]furan-4,9-dione 

Relevant articles and documents

Tandem nucleophilic reaction leading to hydrofurans: Application to one- pot synthesis of antitumor naphthofuran natural product

The reaction of enolates of 1,3-dicarbonyl compounds (1) with 3,4- dibromo-2-butanone (2) afforded hydrofuran derivatives (4) or (5) in the presence of DBU in THF and the reaction was applied to the one-pot synthesis of antitumor naphthofuran products (29).

Domino Michael-O-alkylation reaction: One-pot synthesis of 2,4-diacylhydrofuran derivatives and its application to antitumor naphthofuran synthesis

The one-pot synthesis of 2,4-diacylhydrofuran derivatives and its applications to antitumor napthofuran synthesis was discussed. It was found that the reaction of 1,3-dicarbonyl compounds with α-halo-α,β-unsaturated carbonyl compounds afforded 2,4-diacyldihydrofuran derivatives in the presence of DBU in THF. The analysis showed that the applications of the protocol enabled short-step synthesis of antitumor napthofuran natural products.