61203-01-8

Basic information

• Product Name: 3-bromobut-3-en-2-one
• Synonyms: 3-bromobut-3-en-2-one
• CAS NO: 61203-01-8
• Molecular Formula: C₄H₅BrO
• Molecular Weight: 148.9859
• Mol File: 61203-01-8.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 165.9°C at 760 mmHg
• Flash Point: 86.6°C
• Density: 1.493g/cm³
• Vapor Pressure: 1.83mmHg at 25°C
• Refractive Index: 1.471
• CAS DataBase Reference: 3-bromobut-3-en-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromobut-3-en-2-one(61203-01-8)
• EPA Substance Registry System: 3-bromobut-3-en-2-one(61203-01-8)

Safety Data

• Hazardous Substances Data: 61203-01-8(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Canadian Journal of Chemistry, 60, p. 2268, 1982 DOI: 10.1139/v82-322

Upstream product

• 78-94-4 methyl vinyl ketone 
• 67-56-1 methanol 
• 61203-07-4 3-acetyl-2-oxo-γ-butyrolactone 
• 7726-95-6 bromine 
• 83769-09-9 (2-Bromo-3-oxo-butyl)-dimethyl-sulfonium; bromide 
• 104023-23-6 3-bromo-3-phenylselenobutan-2-one 
• 25109-57-3 3,4-dibromobutan-2-one 
• 854258-70-1 (2-bromo-1-methylen-allyl)-methyl ether 

Downstream Products

• 161402-83-1 1-(2,3-dihydroimidazo<2,1-b>thiazol-6-yl)ethanone 
• 726147-66-6 1-[1-bromo-4-(4-methyl-3-pentenyl)-3-cyclohexenyl]ethan-1-one 
• 1359843-45-0 1-(1-cyclohexylaziridin-2-yl)ethanone 
• 31907-94-5 1-(1-benzylaziridin-2-yl)ethan-1-one 
• 83280-65-3 2-acetylnaphtho[2,3-b]furan-4,9-quinone 
• 147568-55-6 2-acetyl-2,3,4,9-tetrahydronaphtho[2,3-b]furan-4,9-dione 
• 2048-69-3 5-acetyl-3-phenylisoxazole 
• 41850-71-9 4-(p-Anisoxy)-3-buten-2-on 

Relevant articles and documents

Captodative Formyl- and Acyl(amino)alkenes Containing a Terminal Double Bond or a Weakly Basic Tertiary Amino Group

Piperidine reacts with 3-bromo-3-buten-2-one to give a mixture of 3,4-dipiperidinobutan-2-one and 3-piperidino-3-buten-2-one. The latter is also formed by the action of a strong base (Et3N in THF or MeONa in MeOH) on the dipiperidino derivative. Analogous reaction of 2-bromo-3-phenylpropenal with N-methylaniline affords 2-[methyl(phenyl)amino]-3-phenylpropenal which is the first captodative formyl-(amino)alkene having a weakly basic tertiary amino group.

2-ACETYLNAPHTHO[2,3-B]FURAN -4,9-DIONE FOR USE ON TREATING CANCER

The invention provides naphthofuran compounds, polymorphs of naphthofuran compounds, naphthofuran compounds in particle form, purified compositions that contain one or more naphthofuran compounds, purified compositions that contain one or more naphthofuran compounds in particle form, and methods of using these naphthofuran compounds, polymorphs, purified compositions and/or particle forms to treat subjects in need thereof.

Compounds and compositions for targeting cancer stem cells

The invention provides naphthofuran compounds, polymorphs of naphthofuran compounds, naphthofuran compounds in particle form, purified compositions that contain one or more naphthofuran compounds, purified compositions that contain one or more naphthofuran compounds in particle form, methods of producing these naphthofuran compounds, polymorphs, purified compositions and/or particle forms, and methods of using these naphthofuran compounds, polymorphs, purified compositions and/or particle forms to treat subjects in need thereof.