147568-66-9

Basic information

• Product Name: 8-hydroxy-5-[1-hydroxy-2-[2-(4-methoxyphenyl)propan-2-ylamino]ethyl]-1H-quinolin-2-one
• Synonyms: 8-hydroxy-5-[1-hydroxy-2-[2-(4-methoxyphenyl)propan-2-ylamino]ethyl]-1H-quinolin-2-one;8-Hydroxy 5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone;8-Hydroxy-5-[(R)-1-hydroxy-2-[[(R)-1-methyl-2-(4-methoxyphenyl)ethyl]amino]ethyl]quinolin-2(1H)-one;Carmoterol;CHF 4226;CarMotelrol;8-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-Methoxyphenyl)propan-2-yl)aMino)ethyl)quinolin-2(1H)-one;8-Hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-Methoxyphenyl)-1-Methylethyl]aMino]ethyl]-2(1H)-quinolinone CarMoterol
• CAS NO: 147568-66-9
• Molecular Formula: C21H24N2O4
• Molecular Weight: 368.43
• EINECS: 1312995-182-4
• Mol File: 147568-66-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 634.487 °C at 760 mmHg
• Flash Point: 337.526 °C
• Appearance: /
• Density: 1.248
• Vapor Pressure: 5.71E-17mmHg at 25°C
• Refractive Index: 1.611
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 8.68±0.20(Predicted)
• CAS DataBase Reference: 8-hydroxy-5-[1-hydroxy-2-[2-(4-methoxyphenyl)propan-2-ylamino]ethyl]-1H-quinolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-hydroxy-5-[1-hydroxy-2-[2-(4-methoxyphenyl)propan-2-ylamino]ethyl]-1H-quinolin-2-one(147568-66-9)
• EPA Substance Registry System: 8-hydroxy-5-[1-hydroxy-2-[2-(4-methoxyphenyl)propan-2-ylamino]ethyl]-1H-quinolin-2-one(147568-66-9)

Safety Data

• Hazardous Substances Data: 147568-66-9(Hazardous Substances Data)

Usage

General Description

8-hydroxy-5-[1-hydroxy-2-[2-(4-methoxyphenyl)propan-2-ylamino]ethyl]-1H-quinolin-2-one is a chemical compound with a complex structure that includes a quinolinone core and a substituted aminoethyl side chain. It contains hydroxy and methoxy groups, as well as a phenyl ring. 8-hydroxy-5-[1-hydroxy-2-[2-(4-methoxyphenyl)propan-2-ylamino]ethyl]-1H-quinolin-2-one may have potential pharmacological activity due to its structural features, such as the presence of a quinolinone moiety, which has been identified as a pharmacophore in various bioactive compounds. The presence of the substituted aminoethyl side chain also suggests possible interactions with biological targets, making it a potentially interesting compound for further investigation in medicinal chemistry and drug development.

InChI:InChI=1/C21H24N2O4/c1-21(2,13-4-6-14(27-3)7-5-13)22-12-18(25)15-8-10-17(24)20-16(15)9-11-19(26)23-20/h4-11,18,22,24-25H,12H2,1-3H3,(H,23,26)

Upstream product

• 1052689-06-1 8-benzyloxy-5-{(1 S)-1-hydroxy-2-[N-((1R)-2-(p-methoxyphenyl)-1-methylethyl)amino]ethyl}carbostyril hydrochloride 
• 100429-06-9 8-benzyloxy-5-{(1R)-1-hydroxy-2-[N-((1R)-2-(p-methoxyphenyl)-1-methylethyl)amino]ethyl}carbostyril 

Relevant articles and documents

Bronchodilating 8-hydroxy-5-{(1R)-1-hydroxy-2-[N-((1R)-2-(p-methoxyphenyl)-1-methylethyl)-amino]ethyl} carbostyril

A novel carbostyril derivative of the formula: STR1 or a pharmaceutically acceptable acid addition salt thereof, and a process for preparing same. The compound (I) shows potent bronchodilating activity and is useful as a bronchodilator.