4885-02-3 Usage
Description
1,1-Dichlorodimethyl ether is a colorless liquid that serves as a common formylating reagent for aromatic compounds, a chlorinating agent for carboxylic acids, and a reactant with borinic esters for the preparation of alkenones.
Uses
Used in Chemical Synthesis:
1,1-Dichlorodimethyl ether is used as a formylating reagent for aromatic compounds, facilitating the introduction of a formyl group (-CHO) to the aromatic ring, which is crucial for the synthesis of various organic compounds.
Used in Chemical Modification:
As a chlorinating agent for carboxylic acids, 1,1-Dichlorodimethyl ether is employed to introduce a chlorine atom to the carboxylic acid group, which can be further utilized in the synthesis of different chemical products.
Used in the Preparation of Alkenones:
1,1-Dichlorodimethyl ether is used as a reactant with borinic esters to produce alkenones, which are important intermediates in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1,1-Dichlorodimethyl ether is used as a key intermediate in the synthesis of various drugs, taking advantage of its versatile reactivity and ability to formyl or chlorinate other molecules.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, 1,1-Dichlorodimethyl ether is utilized as a starting material or intermediate in the production of various agrochemicals, such as pesticides and herbicides, due to its unique chemical properties.
Check Digit Verification of cas no
The CAS Registry Mumber 4885-02-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,8,8 and 5 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4885-02:
(6*4)+(5*8)+(4*8)+(3*5)+(2*0)+(1*2)=113
113 % 10 = 3
So 4885-02-3 is a valid CAS Registry Number.
InChI:InChI=1/C2H4Cl2O/c1-5-2(3)4/h2H,1H3
4885-02-3Relevant articles and documents
On the Stereochemistry of 2,6-Dichloro-4-methoxy-heptanes
Meusinger, Reinhard,Duschek, Christian,Kleinpeter, Erich,Borsdorf, Rolf,Pihlaja, Kalevi,Mattinen, Jorma
, p. 1019 - 1026 (1988)
2,6-Dichloro-4-methoxy-heptanes may exist as 2 optical active isomers and 2 meso compounds.By double addition of α,α-dichloro-dimethylether to propene a mixture of these stereoisomers was obtained.They were separated by HPLC.Using 1H- and 13C-NMR-spectroscopy their configuration could be established. - Keywords: 2,6-Dichloro-4-methoxy-heptanes; Stereoisomers; NMR-Spectroscopy; Configurational assignment
Convenient preparation of dichloromethyl alkyl ethers
Kimura, Yoshikazu,Warashina, Takuya
, p. 4598 - 4599 (2017/11/15)
Dichloromethyl alkyl ethers have been synthesized from alkyl formates (C1–C4) and oxalyl chloride in the presence of catalytic amount of N-methylformanilide. N,N-Dimethylformamide is not suitable for the reaction. The method has the advantages of simple experimental procedure, which is applicable to large scale synthesis, without use of harmful reagents.
Process for the preparation of methyl 1,1-dichloromethyl ether or of ethyl 1,1-dichloromethyl ether
-
, (2008/06/13)
The invention relates to a process for the preparation of methyl 1,1-dichloromethyl ether or of ethyl 1,1-dichloromethyl ether, according to which methyl formate or ethyl formate is reacted with phosgene, diphosgene, triphosgene or oxalyl chloride or one of their mixtures, at a temperature of between 40° C. and 100° C., in the presence of a catalyst chosen from the group consisting of trisubstituted phosphine oxides and sulphides, trisubstituted phosphine dichlorides, formamides, the products of reaction of formamides with chlorinating agents and mixtures thereof. The 1,1-dichloromethyl ethers are obtained in a high purity. They are useful especially for performing the formylation of aromatic compounds.