147591-63-7Relevant academic research and scientific papers
1-ACETYL-2-CHLORO-3-IMINOINDOLINE HYDROCHLORIDE AND ITS N-ACETYL DERIVATIVES IN NUCLEOPHILIC SUBSTITUTION REACTIONS
Velezheva, V. S.,Ryabova, S. Yu.,Mel'man, A. I.,Pol'shakov, V. I.
, p. 43 - 47 (1992)
It is shown that the chlorine atom in position 2 of 1-acetyl-2-chloro-3-iminoindoline hydrochloride is readily substituted on treatment with secondary amines and thiophenol.The products of nucleophilic reaction are isolated as 2-substituted 3-aminoindoles or 3-acetylaminoindoles, and as 2-substituted 1-acetyl-3-indolinones.The latter are also formed from 1-acetyl-3-indolinone by successive bromination and treatment with secondary amines.
