Chemistry of Heterocyclic Compounds p. 43 - 47 (1992)
Update date:2022-09-26
Topics:
Velezheva, V. S.
Ryabova, S. Yu.
Mel'man, A. I.
Pol'shakov, V. I.
It is shown that the chlorine atom in position 2 of 1-acetyl-2-chloro-3-iminoindoline hydrochloride is readily substituted on treatment with secondary amines and thiophenol.The products of nucleophilic reaction are isolated as 2-substituted 3-aminoindoles or 3-acetylaminoindoles, and as 2-substituted 1-acetyl-3-indolinones.The latter are also formed from 1-acetyl-3-indolinone by successive bromination and treatment with secondary amines.
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(1993)Doi:10.1246/bcsj.66.984
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(1989)Doi:10.1002/hlca.19930760110
(1993)
