147596-60-9

Upstream product

• 51787-96-3 5-(4-fluorophenyl)dihydrofuran-2(3H)-one 
• 4861-79-4 magnesium methyl carbonate 
• 14171-36-9 methyl magnesium carbonate 

Downstream Products

• 148133-85-1 cis/trans-5-(4-Fluorphenyl)-3-<4-(2-oxo-1-benzimidazolinyl)-piperidinomethyl>-4,5-dihydro-2(3H)-furanon 
• 148133-87-3 cis/trans-3-<4-(4-Chlorphenyl)-4-hydroxy-piperidinomethyl>-5-(4-fluorphenyl)-4,5-dihydro-2(3H)-furanon-hydrochlorid 
• 147596-64-3 5-(4-Fluorphenyl)-3-methylen-4,5-dihydro-2(3H)-furanon 

Relevant academic research and scientific papers

Lactones, XXIII: Synthesis and stereochemistry of 'γ-lactonized' butyrophenone-type neuroleptics

'γ-Lactonized' neuroleptics (1,2a-c) can be obtained by reaction of α-formyl, α-carboxy- and α-methylene-lactones 5-7a,b with amines 8a-c. 6a, 1a-c were cis/trans-mixtures with predominating cis-compounds, 6b, 2a cis/trans-mixtures with predominating tran

An improved procedure for α-methylenation of lactones

A variety of γ-butyrolactones, as well as a δ-valerolactone and an ester, have been efficiently converted to their α-methylene derivatives by using an improved decarboxylative methylenation procedure, which is simpler and more general than the previously