4861-79-4Relevant academic research and scientific papers
BIOSYNTHESIS OF CANNABINOID PRODRUGS AND THEIR USE AS THERAPEUTIC AGENTS
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Paragraph 0200, (2017/11/07)
The present invention provides methods for producing cannabinoid prodrugs. Also described are pharmaceuticals acceptable compositions of the prodrugs and a system for the large-scale production of the prodrugs.
METHODS FOR THE MANUFACTURE OF CANNABINOID PRODRUGS, PHARMACEUTICAL FORMULATIONS AND THEIR USE
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Paragraph 0143; 0144, (2018/01/18)
Described are methods for producing cannabinoid prodrugs as well as methods for formulating such prodrugs in a pharmaceutically acceptable form and their use as therapeutic agents for treating diseases.
BIOENZYMATIC SYNTHESIS OF THC-v, CBV AND CBN AND THEIR USE AS THERAPEUTIC AGENTS
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Paragraph 0134; 0135; 0136, (2017/10/18)
The present invention provides methods for producing cannabinoids. More specifically, the invention is directed to the bio-enzymatic synthesis of THC-v, CBV and CBN by contacting a compound according to Formula I with a cannabinoid synthase enzyme. Also described is a system for producing these pharmaceutically important cannabinoids and the use of such cannabinoids as therapeutic agents.
APPARATUS AND METHODS FOR THE SIMULTANEOUS PRODUCTION OF CANNABINOID COMPOUNDS
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Page/Page column 68; 69, (2016/03/22)
The present invention provides an apparatus and methods for simultaneously producing different compounds in various ratios under set conditions.
BIOSYNTHESIS OF CANNABINOIDS
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Paragraph 0127-0129, (2014/09/16)
The present invention provides methods for producing cannabinoids and cannabinoid analogs as well as a system for producing these compounds. The inventive method is directed to contacting a compound according to Formula I or Formula II with a cannabinoid synthase. Also described is a system for producing cannabinoids and cannabinoid analogs by contacting a THCA synthase with a cannabinoid precursor and modifying at least one property of the reaction mixture to influence the quantity formed of a first cannabinoid relative to the quantity formed of a second cannabinoid.
Synthesis and conformational studies on 3-o-tolylhydantoins by NMR and molecular modeling: Dipole-π attractions in peptides and proteins
Park, Sang Hyun,Bose, Ajay K.
, p. 1917 - 1925 (2007/10/03)
5-Pentafluorobenzyl-3-o-tolylhydantoin (2) was synthesized for reducing this π-electron density, and NMR studies have shown that we have succeeded in changing the conformation of 2 into an extended system instead of the folded conformation for the non-fluorinated compound, 5-benzyl-3-o-tolylhydantoin (1). Molecular modeling has also confirmed the extended structure for 2. An approach has been found for possibly modulating the physiological activity of peptides containing aromatic amino acids.
