1476068-40-2Relevant academic research and scientific papers
Discovery of coumarin-dihydroquinazolinone analogs as niacin receptor 1 agonist with in-vivo anti-obesity efficacy
Singh, L. Ravithej,Kumar, Ajeet,Upadhyay, Akanksha,Gupta, Sampa,Palanati, Gopala Reddy,Sikka, Kamakshi,Siddiqi, Mohammad Imran,Yadav, Prem N.,Sashidhara, Koneni V.
supporting information, p. 208 - 222 (2018/05/14)
In this study, we presented rational designing and synthesis of coumarin-dihydroquinazolinone conjugates to evaluate their agonist activity at GPR109a receptor. Among the synthesized small molecule library, compound 10c displayed robust agonist action at
One-pot regioselective synthesis of imidazole and 2,3-dihydroquinazolinone derivatives - An easy access to 'nature-like molecules'; Part XIII in the series: 'Studies on novel synthetic methodologies'
Sashidhara, Koneniv.,Palnati, Gopalareddy,Dodda, Rangaprasad,Avula, Srinivasarao,Swami, Priyanka
, p. 1795 - 1800 (2013/09/12)
A mild and highly practical regioselective synthesis of imidazole and 2,3-dihydroquinazolinone derivatives from 5-alkyl-4-hydroxyisophthalaldehydes with suitable substrates in acetic acid is reported. Further exploration of the molecular diversity of 2,3-dihydroquinazolinone is demonstrated by the synthesis of diverse pharmacologically relevant natural-product-like scaffolds. Georg Thieme Verlag Stuttgart · New York.
