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2-phenyldihydro-2H-pyran-4(3H)-one is a chemical compound characterized by its molecular formula C11H10O2. It is a white to off-white crystalline solid with a molecular weight of 174.2 g/mol. 2-phenyldihydro-2H-pyran-4(3H)-one is recognized for its potential as a building block in the synthesis of pharmaceuticals and natural products, and it is valued for its diverse range of biological activities, including antimicrobial, antifungal, and antitumor properties. Its versatile nature and potential pharmacological applications make it a subject of interest for researchers in medicinal chemistry and drug discovery.

147688-62-8

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147688-62-8 Usage

Uses

Used in Pharmaceutical Synthesis:
2-phenyldihydro-2H-pyran-4(3H)-one is used as a key building block for the synthesis of various pharmaceuticals and natural products. Its structural features make it a valuable component in the development of new drugs.
Used in Organic Synthesis:
In the field of organic synthesis, 2-phenyldihydro-2H-pyran-4(3H)-one is utilized as a versatile intermediate, contributing to the creation of complex organic molecules and compounds.
Used in Medicinal Chemistry:
2-phenyldihydro-2H-pyran-4(3H)-one is employed as a starting material in medicinal chemistry for the exploration of its biological activities and potential therapeutic applications.
Used in Antimicrobial Applications:
2-phenyldihydro-2H-pyran-4(3H)-one is used as an antimicrobial agent, leveraging its ability to combat microbial infections, which is crucial in the development of new antibiotics.
Used in Antifungal Applications:
In antifungal applications, 2-phenyldihydro-2H-pyran-4(3H)-one is utilized for its potential to inhibit fungal growth, making it a candidate for treating fungal infections.
Used in Antitumor Applications:
2-phenyldihydro-2H-pyran-4(3H)-one is used as an antitumor agent, with research focusing on its potential to inhibit tumor growth and its application in cancer therapy.
Used in Drug Discovery:
Due to its diverse biological activities, 2-phenyldihydro-2H-pyran-4(3H)-one is used in drug discovery processes to identify new lead compounds and potential therapeutic agents for various diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 147688-62-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,6,8 and 8 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 147688-62:
(8*1)+(7*4)+(6*7)+(5*6)+(4*8)+(3*8)+(2*6)+(1*2)=178
178 % 10 = 8
So 147688-62-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H12O2/c12-10-6-7-13-11(8-10)9-4-2-1-3-5-9/h1-5,11H,6-8H2

147688-62-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Phenyldihydro-2H-pyran-4(3H)-one

1.2 Other means of identification

Product number -
Other names 2-phenyloxan-4-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:147688-62-8 SDS

147688-62-8Relevant academic research and scientific papers

A novel self-terminated Prins strategy for the synthesis of tetrahydropyran-4-one derivatives and their behaviour in Fisher indole synthesis

Reddy, B. V. Subba,Anjum, S. Rehana,Sridhar

, p. 75133 - 75137 (2016/08/24)

A novel self-terminated Prins strategy has been developed for the synthesis of 2-substituted tetrahydropyran-4-one derivatives through a condensation of 3-(phenylthio)but-3-en-1-ol with carbonyl compounds in the presence of 5 mol% of Sc(OTf)3 u

Mechanistic analysis of oxidative C-H cleavages using inter- and intramolecular kinetic isotope effects

Jung, Hyung Hoon,Floreancig, Paul E.

experimental part, p. 10830 - 10836 (2010/02/28)

A series of monodeuterated benzylic and allylic ethers were subjected to oxidative carbon-hydrogen bond cleavage to determine the impact of structural variation on intramolecular kinetic isotope effects in DDQ-mediated cyclization reactions. These values

NOVEL PIPERIDINYL-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONES AS M1 AGONISTS

-

Page/Page column 36, (2009/11/29)

The present invention relates to novel M1 agonistic compounds of the present invention and their use in the treatment of cognitive impairment associated i.a. with schizophrenia and in the treatment of other diseases mediated by the muscarinic M1 receptor.

Enzymes in Organic Synthesis. 25. Heterocyclic Ketones as Substrates of Horse Liver Alcohol Dehydrogenase. Highly Stereoselective Reductions of 2-Substituted Tetrahydropyran-4-ones

Haslegrave, J. Anthony,Jones, J. Bryan

, p. 4666 - 4671 (2007/10/02)

Horse liver alcohol dehydrogenase (HLADH) has been found to be an efficient catalyst for the reduction of O-heterocyclic ketones.Preparative-scale HLADH-catalyzed reductions of 2-substituted tetrahydropyran-4-ones are enantioselective, with reduction of e

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