14769-29-0

Basic information

• Product Name: ethyl N-[(benzyloxy)carbonyl]glycyl-O-ethyl-3-oxoserinate
• CAS NO: 14769-29-0
• Molecular Formula: C₁₇H₂₂N₂O₇
• Molecular Weight: 366.3658
• Mol File: 14769-29-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 535.4°C at 760 mmHg
• Flash Point: 277.6°C
• Density: 1.236g/cm³
• Vapor Pressure: 1.55E-11mmHg at 25°C
• Refractive Index: 1.519
• CAS DataBase Reference: ethyl N-[(benzyloxy)carbonyl]glycyl-O-ethyl-3-oxoserinate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl N-[(benzyloxy)carbonyl]glycyl-O-ethyl-3-oxoserinate(14769-29-0)
• EPA Substance Registry System: ethyl N-[(benzyloxy)carbonyl]glycyl-O-ethyl-3-oxoserinate(14769-29-0)

Safety Data

• Hazardous Substances Data: 14769-29-0(Hazardous Substances Data)

Upstream product

• 6829-40-9 aminomalonic acid diethyl ester 
• 15050-24-5 N-(benzyloxycarbonyl)glycyl chloride 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 13433-00-6 diethyl aminomalonate hydrochloride 

Downstream Products

• 100317-70-2 3-(2-ethoxycarbonyl-3,6-dioxo-piperazin-2-yl)-propionic acid ethyl ester 
• 98142-97-3 3,6-dioxopiperazine-2-carboxamide 
• 86750-34-7 3-Ethoxycarbonyl-piperazin-2,5-dion 
• 14811-38-2 [(N-benzyloxycarbonyl-glycyl)-amino]-malonic acid 

Relevant articles and documents

PERIPHERALLY RESTRICTED GABA POSITIVE ALLOSTERIC MODULATORS FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME AND OTHER AILMENTS OF THE PERIPHERAL NERVOUS SYSTEM

The present invention provides compounds and compositions which are positive allosteric modulators of GABA-A receptors that selectively target the peripheral nervous system and organs of the body, and which do not pass through the blood-brain barrier. The compounds and compositions of the present invention are useful for treatment of diseases or disorders which are mediated by GABA-A neuronal activity, such as, for example, visceral pain, gut motility, irritable bowel syndrome, functional abdominal pain, functional idiopathic diarrhea, inflammatory bowel diseases, drug induced pain, bile salt malabsorption, lactase or other carbohydrate intolerance.