98142-97-3

Basic information

• Product Name: 2-Piperazinecarboxamide,3,6-dioxo-(6CI)
• Synonyms: 2-Piperazinecarboxamide,3,6-dioxo-(6CI)
• CAS NO: 98142-97-3
• Molecular Formula: C5H7N3O3
• Molecular Weight: 157.12738
• Product Categories: AMIDE
• Mol File: 98142-97-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Piperazinecarboxamide,3,6-dioxo-(6CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Piperazinecarboxamide,3,6-dioxo-(6CI)(98142-97-3)
• EPA Substance Registry System: 2-Piperazinecarboxamide,3,6-dioxo-(6CI)(98142-97-3)

Safety Data

• Hazardous Substances Data: 98142-97-3(Hazardous Substances Data)

Upstream product

• 41394-71-2 2-(chloroacetylamino)propanedioic acid diethyl ester 
• 14769-29-0 diethyl 2-[[2-(benzyloxycarbonylamino)acetyl]amino]propanedioate 
• 86750-34-7 3-Ethoxycarbonyl-piperazin-2,5-dion 

Downstream Products

• 356783-31-8 6-fluoro-3-hydroxypyrazine-2-carbonitrile 
• 356783-16-9 3,6-dichloropyrazine-2-carbonitrile 
• 356783-28-3 3,6-difluoropyrazine-2-carbonitrile 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF 3,6-DICHLOROCYANO PYRAZINE, 3,6-DIOXOPIPERAZINE DERIVATIVES AND PRODUCTION OF FAVIPIRAVIR THEREOF

The present invention relates to a method of preparing derivatives of 3,6-dichlorocyano pyrazine, 3,6-dioxopiperizin and the production of favipiravir by cyclization and chlorination mediated by ammonia or amine using POCl3 in the presence of pyridine or PCl5. [Formula] In derivatives of 3,6-dioxopiperazine (III), X represents CN, CONH2 or COOR2', R1, R 2 and R2' are individually selected from H, alkyl C1-C12, COOR3 and SO2R3, R 3 being a linear or branched lower alkyl substituted or unsubstituted.