14774-35-7

Basic information

• Product Name: 5,6-dihydro-2H-pyran-3-methanol
• Synonyms: 5,6-dihydro-2H-pyran-3-methanol;Einecs 238-840-7;(5,6-Dihydro-2H-pyran-3-yl)-Methanol;3,6-dihydro-2H-pyran-5-ylMethanol
• CAS NO: 14774-35-7
• Molecular Formula: C6H10O2
• Molecular Weight: 114.1424
• EINECS: 238-840-7
• Mol File: 14774-35-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 211°Cat760mmHg
• Flash Point: 94.5°C
• Appearance: /
• Density: 1.063g/cm³
• Vapor Pressure: 0.0423mmHg at 25°C
• Refractive Index: 1.479
• CAS DataBase Reference: 5,6-dihydro-2H-pyran-3-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-dihydro-2H-pyran-3-methanol(14774-35-7)
• EPA Substance Registry System: 5,6-dihydro-2H-pyran-3-methanol(14774-35-7)

Safety Data

• Hazardous Substances Data: 14774-35-7(Hazardous Substances Data)

Usage

General Description

5,6-dihydro-2H-pyran-3-methanol is a chemical compound with the molecular formula C6H10O2. It is a colorless liquid with a sweet odor, and it is commonly used in the production of fragrances and flavoring agents. It is also known for its potential applications in organic synthesis and pharmaceutical research. The compound is predominantly used as a precursor in the synthesis of various pharmaceuticals and natural products. Additionally, it is utilized in the manufacturing of pesticides and as a building block in the synthesis of complex organic molecules. Overall, 5,6-dihydro-2H-pyran-3-methanol is a versatile chemical compound with various industrial and research applications.

InChI:InChI=1/C6H10O2/c7-4-6-2-1-3-8-5-6/h2,7H,1,3-5H2

Upstream product

• 13417-49-7 5,6-dihydro-2H-pyran-3-carbaldehyde 

Downstream Products

• 106273-64-7 3,5-dinitro-benzoic acid-(5,6-dihydro-2H-pyran-3-ylmethyl ester) 
• 756533-15-0 4-methoxy-benzoic acid 5,6-dihydro-2H-pyran-3-ylmethyl ester 
• 92844-01-4 3-((3E,7E)-10-Hydroxy-7-methyl-deca-3,7-dienyl)-4-methyl-cyclohex-3-enol 
• 92829-90-8 [(3E,7E)-10-(5-Benzyloxy-2-methyl-cyclohex-1-enyl)-4-methyl-deca-3,7-dienyloxy]-tert-butyl-dimethyl-silane 
• 92829-91-9 Toluene-4-sulfonic acid (3E,7E)-10-(5-hydroxy-2-methyl-cyclohex-1-enyl)-4-methyl-deca-3,7-dienyl ester 
• 14774-36-8 rac-(tetrahydro-2H-pyran-3-yl)methanol 
• 1622081-74-6 5-(2,4,6-trimethylbenzyl)-3,6-dihydro-2H-pyran 

Relevant articles and documents

STEREOSPECIFIC SYSNTHESIS OF (+/-)-β-SANTALOL

A sterospecific sysnthesis of 1-acetoxy-5-bromo-2-methyl-2-cis-pentene in 4 steps starting from 3-formyl-5,6-dihydro-2H-pyran, dimer of acrolein, followed by alkylation of 2-ethoxycarbonyl-3-methylbicyclo(2.2.1)hept-2-ene with the bromide furnished a facile sysnthesis of (+/-)-β-santalol.

Chiral hetero- and carbocyclic compounds from the asymmetric hydrogenation of cyclic alkenes

Several types of chiral hetero- and carbocyclic compounds have been synthesized by using the asymmetric hydrogenation of cyclic alkenes. N,P-Ligated iridium catalysts reduced six-membered cyclic alkenes with various substituents and heterofunctionality in good to excellent enantioselectivity, whereas the reduction of five-membered cyclic alkenes was generally less selective, giving modest enantiomeric excesses. The stereoselectivity of the hydrogenation depended more strongly on the substrate structure for the five- rather than the six-membered cyclic alkenes. The major enantiomer formed in the reduction of six-membered alkenes could be predicted from a selectivity model and isomeric alkenes had complementary enantioselectivity, giving opposite optical isomers upon hydrogenation. The utility of the reaction was demonstrated by using it as a key step in the preparation of chiral 1,3-cis-cyclohexane carboxylates. Copyright