147745-25-3

Upstream product

• 68277-01-0 2-amino-3-oxo-butyric acid methyl ester 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 41172-77-4 (±)-2-amino-3-oxo-butyric acid methyl ester hydrochloride 

Downstream Products

• 1257861-35-0 (S)-methyl 2-(1-((tert-butoxycarbonyl)amino)-2-phenylethyl)-5-methyloxazole-4-carboxylate 
• 479666-62-1 2-(1-tert-butoxycarbonylamino-2-phenyl-ethyl)-1,5-dimethyl-1H-imidazole-4-carboxylic acid 
• 479666-59-6 2-(1-tert-butoxycarbonylamino-2-phenyl-ethyl)-1,5-dimethyl-1H-imidazole-4-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of a new class of imidazole-based cyclic peptides

A new class of cyclic peptides based on dipeptidyl imidazoles is presented. Their structure consists of imidazole units alternating with standard amino acid residues and resembles naturally occurring marine cyclopeptides such as westiellamide and ascidiacyclamide.

An efficient synthesis and acylation of α-amino-β-keto-esters: Versatile intermediates in the synthesis of peptide mimetics

A flexible and high yield synthesis of α-amino-β-keto esters has been developed via acylation of the ketimine derivatives of α-amino esters. These α-amino-β-keto-esters were acylated with chiral amino acid derivatives in 36-95% yields.