68277-01-0

Basic information

• Product Name: Methyl 2-amino-3-oxobutanoate
• Synonyms: methyl 2-amino-3-oxobutanoate;2-amino-3-oxobutanoic acid methyl ester;Butanoic acid, 2-amino-3-oxo-, methyl ester (9CI);Butanoic acid, 2-amino-3-oxo-, methyl ester;Methyl2-aMino-3-oxobutanoatehydrochloride
• CAS NO: 68277-01-0
• Molecular Formula: C₅H₉NO₃
• Molecular Weight: 131.13
• Product Categories: ACETYLGROUP
• Mol File: 68277-01-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 85-86°C
• Boiling Point: 167.5°C
• Flash Point: 51.4°C
• Appearance: /
• Density: 1.133
• Vapor Pressure: 1.692mmHg at 25°C
• Refractive Index: 1.44
• Storage Temp.: 2-8°C
• PKA: 14.17±0.59(Predicted)
• CAS DataBase Reference: Methyl 2-amino-3-oxobutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-amino-3-oxobutanoate(68277-01-0)
• EPA Substance Registry System: Methyl 2-amino-3-oxobutanoate(68277-01-0)

Safety Data

• Hazardous Substances Data: 68277-01-0(Hazardous Substances Data)

Usage

General Description

Methyl 2-amino-3-oxobutanoate, also known as Methyl N-Carbobenzyloxy-Aspartate and Methyl-2-amino-isovaleric Acid Methyl Ester, belongs to the class of organic compounds known as L-alpha-amino acids. It is identified by its molecular formula C6H11NO3. This chemical has applications in scientific research, specifically in the field of biochemistry where it is frequently used in the synthesis of peptides. Its toxicity or hazard details are not well-studied; therefore, care should be taken when handling this compound. Methyl 2-amino-3-oxobutanoate is generally sold as a light yellow to brown liquid, and should be stored in cool, dry conditions.

InChI:InChI=1/C5H9NO3/c1-3(7)4(6)5(8)9-2/h4H,6H2,1-2H3

Upstream product

• 29291-62-1 methyl 2-nitro-acetoacetate 
• 105-45-3 acetoacetic acid methyl ester 
• 124576-57-4 C₁₀H₁₇NO₅ 
• 41172-57-0 5-Methyloxazol-4-carbonsaeure-methylester 
• 73708-95-9 methyl 3-oxo-2-oximinobutanoate 

Downstream Products

• 98432-01-0 methyl 2-acetamido-3-oxobutanoate 
• 952029-14-0 C₇H₁₁NO₅ 
• 156571-70-9 α-Benzyloxycarbonylamino-acetessigsaeuremethylester 
• 77320-41-3 2-benzoylamino-3-oxo-butyric acid methyl ester 
• 952029-32-2 C₁₆H₁₉NO₅ 
• 952029-40-2 C₁₆H₂₁NO₅ 
• 223561-11-3 (E)-(R)-2-Acetyl-2-acetylamino-5-phenyl-pent-4-enoic acid methyl ester 
• 1413476-68-2 C₁₃H₁₁NO₅ 
• 479666-60-9 2-(2-benzyloxycarbonylamino-1-tert-butoxycarbonylamino-ethyl)-1,5-dimethyl-1H-imidazole-4-carboxylic acid methyl ester 
• 479666-59-6 2-(1-tert-butoxycarbonylamino-2-phenyl-ethyl)-1,5-dimethyl-1H-imidazole-4-carboxylic acid methyl ester 
• 479666-57-4 2-(3-benzyloxycarbonylamino-2-tert-butoxycarbonylamino-propionylamino)-3-oxo-butyric acid methyl ester 
• 147745-25-3 methyl 2-((S)-2-(tert-butoxycarbonylamino)-3-phenylpropanamido)-3-oxobutanoate 

Relevant articles and documents

Synthesis method for 2-formyl-3,4-dimethyl-5-acetyl pyrrole

The invention discloses a synthesis method for 2-formyl-3,4-dimethyl-5-acetyl pyrrole, and belongs to the field of chemical synthesis. The synthesis method comprises the steps that acetic anhydride is taken as a raw material, glacial acetic acid is added into the acetic anhydride, and sodium nitrite is dropwise added by controlling the temperature for a reaction; after the reaction is finished, acetylacetone and zinc powder are added, a reaction is performed after the pH value is regulated, and cooling crystallizing and suction filtering are performed after the reaction is finished; filter residues are cleaned and recrystallized with petroleum ether to obtain 2,5-diacetyl-3,4-dimethyl pyrrole, the 2,5-diacetyl-3,4-dimethyl pyrrole is taken to be dissolved in glacial acetic acid, and sulfuryl chloride is dropwise added into the mixture for a reaction; cooling crystallizing, suction filtering and drying are performed, and then the 2-formyl-3,4-dimethyl-5-acetyl pyrrole is obtained.