147776-85-0

Upstream product

• 423-39-2 1-iodo-2,2,3,3,4,4,5,5,5-nonafluorobutane 
• 103-26-4 Methyl cinnamate 
• 286858-47-7 (E)-5-ethoxy-1,1,1,2,2,3,3,4,4-nonafluoro-6-(phenylseleno)hex-5-ene 
• 4192-77-2 ethyl cinnamate 
• 424-36-2 2,2,3,3,4,4,5,5,5-nonafluoropentanoic acid ethyl ester 
• 286858-74-0 (Z)-5-ethoxy-1,1,1,2,2,3,3,4,4-nonafluoro-7-phenylhept-5-en-7-ol 

Downstream Products

• 90550-17-7 4,4,5,5,6,6,7,7,7-Nonafluoro-1-phenyl-heptan-3-one 
• 90550-20-2 (R)-4,4,5,5,6,6,7,7,7-Nonafluoro-1-phenyl-heptan-3-ol 
• 90550-20-2 (S)-4,4,5,5,6,6,7,7,7-Nonafluoro-1-phenyl-heptan-3-ol 

Relevant academic research and scientific papers

A new entry for the oxidation of fluoroalkyl-substituted methanol derivatives: Scope and limitation of the organoiodine(V) reagent-catalyzed oxidation

Oxidation of various fluoroalkyl-substituted methanol derivatives under the influence of a catalytic amount of sodium 2-iodobenzenesulfonate and Oxone in CH3CN or CH3NO2 was investigated in detail. The efficiency of the newly developed oxidation was also evaluated by comparison to other oxidations, such as Dess-Martin, PDC, and Swern oxidation.

The reaction of carboxylic acid esters with RfMgBr: A convenient synthesis of perfluoroalkyl ketones

An efficient method for the preparation of the synthetically attractive perfluoroalkyl ketones through the reaction of readily available alkenoates, alkynoates, or regular carboxylic esters with perfluoroalkyl Grignard reagents at -70 to -60 °C in diethyl

Preparation of Perfluoroalkyl Ketones by the Reaction of Perfluoroalkyllithiums with Esters

A variety of esters react with perfluoroalkyllithiums in situ generated from perfluoroalkyl iodides and methyllithium to give perfluoroalkyl ketones in good yields.Perfluoroalkyllithiums add to α,β-unsaturated esters only in the 1,2-addition mode even in the presence of copper salt.Exception was observed in the reaction with maleates where perfluoroalkylated succinic esters and normal 1,2-addition products are obtained in comparable amounts.

An Efficient Synthesis of Perfluoroalkyl Ketones Using Perfluoroalkyllithiums

Perfluoroalkylation of esters with perfluoroalkyllithiums occurs smoothly in ether at -78 deg C, giving the corresponding perfluoroalkyl ketones in good yields.