1477816-25-3

Upstream product

• 115844-00-3 4-bromo-2-chloro-5-(trifluoromethoxy)phenylamine 
• 1433279-99-2 ((S)-1-{(2S,4S)-2-[5-(4-bromophenyl)-1H-imidazol-2-yl]-4-methylpyrrolidine-1-carbonyl}-2-methylpropyl)carbamic acid methyl ester 
• 1250939-45-7 (2S,4S)-2-[4-(4-bromo-phenyl)-1H-imidazol-2-yl]-4-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 147081-29-6 (S)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester 
• 116369-25-6 4-bromo-3-(trifluoromethoxy)phenylamine 
• 111398-44-8 N-methoxycarbonyl-L-valine 
• 72-18-4 L-valine 
• 1433280-00-2 [(S)-2-methyl-1-((2S,4S)-4-methyl-2-{4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-phenyl]-1H-imidazol-2-yl}-pyrrolidine-1-carbonyl)-propyl]carbamic acid methyl ester 
• 1477815-63-6 (S)-4-[1-(4-bromo-2-chloro-5-trifluoromethoxyphenylcarbamoyl)piperidin-4-yl]-3-methylpiperazinecarboxylic acid tert-butyl ester 
• 1477815-58-9 (S)-3-methyl-4-(piperidin-4-yl)piperazine-1-carboxylic acid tert-butyl ester 
• 1477815-62-5 (S)-4-(1-benzyloxycarbonylpiperidin-4-yl)-3-methylpiperazine-1-carboxylic acid tert-butyl ester 
• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 

Relevant academic research and scientific papers

PIPERAZINE-PIPERIDINE COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS

The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of replication of the hepatitis C virus. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat hepatitis C viral infections, and processes and intermediates useful for preparing such compounds.