1477816-43-5

Basic information

• Product Name: {(S)-2-methyl-1-[(2S,4S)-4-methyl-2-(7-{4-[(4-(piperidin-4-yl)piperazine-1-carbonyl)amino]-2-trifluoromethoxyphenyl}-3H-naphtho[1,2-d]imidazol-2-yl)pyrrolidine-1-carbonyl]propyl}carbamic acid methyl ester
• Synonyms: {(S)-2-methyl-1-[(2S,4S)-4-methyl-2-(7-{4-[(4-(piperidin-4-yl)piperazine-1-carbonyl)amino]-2-trifluoromethoxyphenyl}-3H-naphtho[1,2-d]imidazol-2-yl)pyrrolidine-1-carbonyl]propyl}carbamic acid methyl ester
• CAS NO: 1477816-43-5
• Molecular Weight: 778.875
• Mol File: 1477816-43-5.mol

Chemical Properties

• CAS DataBase Reference: {(S)-2-methyl-1-[(2S,4S)-4-methyl-2-(7-{4-[(4-(piperidin-4-yl)piperazine-1-carbonyl)amino]-2-trifluoromethoxyphenyl}-3H-naphtho[1,2-d]imidazol-2-yl)pyrrolidine-1-carbonyl]propyl}carbamic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {(S)-2-methyl-1-[(2S,4S)-4-methyl-2-(7-{4-[(4-(piperidin-4-yl)piperazine-1-carbonyl)amino]-2-trifluoromethoxyphenyl}-3H-naphtho[1,2-d]imidazol-2-yl)pyrrolidine-1-carbonyl]propyl}carbamic acid methyl ester(1477816-43-5)
• EPA Substance Registry System: {(S)-2-methyl-1-[(2S,4S)-4-methyl-2-(7-{4-[(4-(piperidin-4-yl)piperazine-1-carbonyl)amino]-2-trifluoromethoxyphenyl}-3H-naphtho[1,2-d]imidazol-2-yl)pyrrolidine-1-carbonyl]propyl}carbamic acid methyl ester(1477816-43-5)

Safety Data

• Hazardous Substances Data: 1477816-43-5(Hazardous Substances Data)

Upstream product

• 177276-41-4 4-(piperazin-1-yl)piperidine-1-carboxylic acid tert-butyl ester 
• 177276-40-3 4-(1-tert-butoxycarbonylpiperidin-4-yl)piperazine-1-carboxylic acid benzyl ester 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 364750-81-2 N-tert-Butyloxycarbonyl-(2S,4S)-4-methylproline 
• 111398-44-8 N-methoxycarbonyl-L-valine 
• 72-18-4 L-valine 
• 1476720-76-9 {(S)-1-[(2S,4S)-2-(7-bromo-3H-naphtho[1,2-d]imidazol-2-yl)-4-methyl-pyrrolidine-1-carbonyl]-2-methyl-propyl}-carbamic acid methyl ester 
• 1378391-12-8 ((S)-2-methyl-1-{(2S,4S)-4-methyl-2-[7-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3H-naphtho[1,2-d]imidazol-2-yl]-pyrrolidine-1-carbonyl}-propyl)-carbamic acid methyl ester 
• 1326303-51-8 (2S,4S)-2-(7-bromo-3H-naphtho[1,2-d]imidazol-2-yl)-4-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1241377-74-1 6-bromo-naphthalene-1,2-diamine 
• 1476720-74-7 (2S,4S)-2-(2-amino-6-bromo-naphthalen-1-ylcarbamoyl)-4-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1476720-75-8 7-bromo-2-((2S,4S)-4-methyl-pyrrolidin-2-yl)-3H-naphtho[1,2-d]imidazole 
• 1477815-41-0 4-[4-(4-bromo-3-trifluoromethoxyphenylcarbamoyl)piperazin-1-yl]piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

PIPERAZINE-PIPERIDINE COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS

The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of replication of the hepatitis C virus. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat hepatitis C viral infections, and processes and intermediates useful for preparing such compounds.