147895-12-3

Basic information

• Product Name: methyl 4-(3-oxocyclohexyl)butanoate
• CAS NO: 147895-12-3
• Molecular Weight: 198.262
• Mol File: 147895-12-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 4-(3-oxocyclohexyl)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(3-oxocyclohexyl)butanoate(147895-12-3)
• EPA Substance Registry System: methyl 4-(3-oxocyclohexyl)butanoate(147895-12-3)

Safety Data

• Hazardous Substances Data: 147895-12-3(Hazardous Substances Data)

Upstream product

• 113116-57-7 3-(4-oxobutyl) cyclohexanone 
• 930-68-7 cyclohexenone 
• 91253-59-7 3-(4-pentenyl)cyclohexan-1-one 
• 186581-53-3 diazomethane 
• 147932-61-4 4-(3-oxo-cyclohexyl)-butyric acid 

Downstream Products

• 6102-38-1 (4aR,8aS)-8a-methyloctahydronaphthalen-1(2H)-one 
• 92485-95-5 (8R,9R,10R)-8-hydroxy-9-methyl-1-decalone 
• 147976-70-3 (8S,9R,10R)-8-hydroxy-9-methyl-1-decalone 
• 92485-95-5 (8S,9S,10S)-8-hydroxy-9-methyl-1-decalone 

Relevant articles and documents

Preparative Bioorganic Chemistry, XVII. Reduction of a Prochiral Diketone, 9-Methyl-trans-decalin-1,8-dione, with Baker's Yeast

Reduction of 9-methyl-trans-decalin-1,8-dione (1) with baker's yeast affords (8S,9R,10R)-8-hydroxy-9-methyl-trans-1-decalone (8) as the major product in 47percent yield.Its (8S,9S,10S)-isomer (9, 14percent yield) and (1S,8S)-9-methyl-trans-1,8-diol (10, 7percent yield) are obtained as minor products.Baker's yeast cannot reduce 9-methyl-cis-decalin-1,8-dione (2). Key Words: Asymmetric reduction / Baker's yeast / Yeast / Saccharomyces cerevisia / Enzymes / trans-1-Decalone derivatives / trans-1,8-Decalindione derivatives