92485-95-5Relevant academic research and scientific papers
Preparative Bioorganic Chemistry, XVII. Reduction of a Prochiral Diketone, 9-Methyl-trans-decalin-1,8-dione, with Baker's Yeast
Mori, Kenji,Takayama, Shuichi,Yoshimura, Seiji
, p. 91 - 96 (2007/10/02)
Reduction of 9-methyl-trans-decalin-1,8-dione (1) with baker's yeast affords (8S,9R,10R)-8-hydroxy-9-methyl-trans-1-decalone (8) as the major product in 47percent yield.Its (8S,9S,10S)-isomer (9, 14percent yield) and (1S,8S)-9-methyl-trans-1,8-diol (10, 7percent yield) are obtained as minor products.Baker's yeast cannot reduce 9-methyl-cis-decalin-1,8-dione (2). Key Words: Asymmetric reduction / Baker's yeast / Yeast / Saccharomyces cerevisia / Enzymes / trans-1-Decalone derivatives / trans-1,8-Decalindione derivatives
A new enantioselective approach to the bicyclo[4.4.0]decane and bicyclo[4.3.0]nonane systems
Asaoka,Nishimura,Takei
, p. 407 - 411 (2007/10/02)
Highly diasteroselective routes to cis-fused bicyclo[4.4.0]decane-2,10-diones and bicyclo[4.3.0]nonane-2,9-diones from 5-trimethylsilyl-2-cyclohexen-1 -one (1a) and its 3-methyl derivative were established by utilizing an annulation with Ω-(alkoxycarbonyl
PREPARATION OF BYCYCLOOCTANE-2,8-DIONE- AND DECALIN-1,8-DIONE-DERIVATIVES
Duthaler, Rudolf O.,Maienfisch, Peter
, p. 856 - 865 (2007/10/02)
Alkylation of bicyclooctane-2,8-dione (1), which is prepared by a modification of the procedure described in the literature, gives the methyl- and propynyl-derivatives 6 and 7 (Scheme 1).In addition to the method described previously (Scheme 2), 9-
