1479-58-9

Basic information

• Product Name: 2-Amino-2'-fluoro-5-bromobenzophenone
• Synonyms: 2-AMINO-5-BROMO-2'-FLUOROBENZOPHENONE;(2-AMINO-5-BROMO-PHENYL)-(2-FLUORO-PHENYL)-METHANONE;2-AMINO-2'-FLUORO-5-BROMOBENZOPHENONE;Methanone, (2-amino-5-bromophenyl)(2-fluorophenyl)-;2-Amino-2'-fluoro-5-bromobenzophenone,98%;2-Amino-5-bromo-2zzhlxy-fluorobenzophenone;(2-Amino-5-bromophenyl)(2-fluorophenyl)methanone, 4-Bromo-2-(2-fluorobenzoyl)aniline
• CAS NO: 1479-58-9
• Molecular Formula: C₁₃H₉BrFNO
• Molecular Weight: 294.12
• EINECS: 216-037-2
• Product Categories: Aromatic Benzophenones & Derivatives (substituted);API intermediates;Intermediates;Amines;Aromatics
• Mol File: 1479-58-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 100-104 °C
• Boiling Point: 450.9 °C at 760 mmHg
• Flash Point: 226.5 °C
• Appearance: /Solid
• Density: 1.5259 (estimate)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: -1.12±0.10(Predicted)
• Water Solubility: insoluble
• CAS DataBase Reference: 2-Amino-2'-fluoro-5-bromobenzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-2'-fluoro-5-bromobenzophenone(1479-58-9)
• EPA Substance Registry System: 2-Amino-2'-fluoro-5-bromobenzophenone(1479-58-9)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 1479-58-9(Hazardous Substances Data)

Usage

Chemical Properties

yellow powder

Uses

Intermeidate in the preparation of many GABA modulators

Upstream product

• 74189-16-5 2-amino-5-bromobenzoic acid hydrochloride 
• 87-48-9 5-Bromo-1H-indole-2,3-dione 
• 1072-85-1 o-fluorobromobenzene 
• 304854-54-4 2-amino-5-bromo-N-methoxy-N-methyl-benzamide 

Downstream Products

• 2647-50-9 7-bromo-5-(2-fluorophenyl)-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one 
• 1052719-57-9 7-bromo-9-(2-fluorophenyl)-3-(trifluoromethyl)-3,4-dihydroacridin-1(2H)-one 
• 872874-11-8 (R)-7-bromo-5-(2-fluorophenyl)-3-methyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one 
• 872874-12-9 ethyl (R)-8-bromo-6-(2-fluorophenyl)-4-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate 
• 1413433-15-4 (S)-8-ethynyl-6-(2-fluorophenyl)-4-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid 

Relevant articles and documents

Synthesis of Flubromazepam Positional Isomers for Forensic Analysis

Designer benzodiazepines have recently appeared in many forensic cases as legal alternatives to federally scheduled drugs such as diazepam (Valium) and alprazolam (Xanax). Though current forensic instrumental techniques are often sufficient for identifying novel psychoactive substances, they may not readily differentiate between potential positional isomers. Additionally, characterization data for positional isomers of known designer benzodiazepines are widely nonexistent. In this study, flubromazepam, a recognized designer benzodiazepine since 2012, was targeted for synthesis and characterization due to its potential for federal scheduling and current legal status within the United States. A practical synthetic method was developed to prepare purified reference materials for each positional isomer of flubromazepam in which the positions of the bromine and fluorine substituents were varied. Possible isomers (9 of the 12) were successfully prepared and used for further analysis.