147920-22-7 Usage
Chemical compound
2''-amino-2''-deoxyarbekacin
Classification
Aminoglycoside antibiotic
Derived from
Arbekacin
Modification
At the 2'' position of the amino group
Enhanced properties
Improved antibacterial activity and pharmacokinetics
Effectiveness
Potent and effective against various bacterial infections, including multidrug-resistant strains
Mechanism of action
Inhibits protein synthesis in bacteria
Clinical use
Treatment of serious infections where other antibiotics have failed
Demonstrated effectiveness
Shown in clinical trials
Overall assessment
Promising antibiotic with potent antibacterial properties; potential for managing complicated infections.
Check Digit Verification of cas no
The CAS Registry Mumber 147920-22-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,9,2 and 0 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 147920-22:
(8*1)+(7*4)+(6*7)+(5*9)+(4*2)+(3*0)+(2*2)+(1*2)=137
137 % 10 = 7
So 147920-22-7 is a valid CAS Registry Number.
147920-22-7Relevant articles and documents
Dibekacin derivatives and arbekacin derivatives active against resistant bacteria
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, (2008/06/13)
As new dibekacin derivatives and new arbekacin derivatives are now provided 2"-amino-2"-deoxydibekacin, 2"-amino-5,2"-dideoxydibekacin, 2"-amino-2"-deoxyarbekacin, 2"-amino-5,2"-dideoxyarbekacin, 2"-amino-5,2"-dideoxy-5-epi-fluoroarbekacin and 2"-amino-5,2"-dideoxy-5-epi-aminoarbekacin which all exhibit high antibacterial activity against a wide variety of gram-positive and gram-negative bacteria, including resistant bacteria such as methicillin-resistant Staphylococcus aureus and which are of low toxicity to mammals and are useful as antibacterial agent for treatment of bacterial infections.