147923-47-5

Basic information

• Product Name: BOC-D-4,4-BIPHENYLALANINE
• Synonyms: BOC-D-4,4'-BIPHENYLALANINE
• CAS NO: 147923-47-5
• Molecular Formula: C20H23NO4
• Molecular Weight: 428.48
• Mol File: 147923-47-5.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: BOC-D-4,4-BIPHENYLALANINE(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-D-4,4-BIPHENYLALANINE(147923-47-5)
• EPA Substance Registry System: BOC-D-4,4-BIPHENYLALANINE(147923-47-5)

Safety Data

• Hazardous Substances Data: 147923-47-5(Hazardous Substances Data)

Usage

Description

BOC-D-4,4-BIPHENYLALANINE, also known as Boc-D-4,4'-biphenylalanine, is an organic compound that serves as a crucial building block in the synthesis of various pharmaceutical compounds. It is characterized by its unique molecular structure, which features a biphenylalanine backbone protected by a tert-butyloxycarbonyl (Boc) group. This structure endows BOC-D-4,4-BIPHENYLALANINE with potential applications in the development of novel therapeutic agents.

Uses

Used in Pharmaceutical Industry:
BOC-D-4,4-BIPHENYLALANINE is used as a key intermediate in the synthesis of pyrrolopyrimidine inhibitors of Akt, which are considered as antitumor agents. These inhibitors target the Akt protein, a serine/threonine-specific protein kinase that plays a significant role in cell survival, growth, and angiogenesis. By inhibiting Akt, these compounds can potentially suppress tumor growth and progression.
BOC-D-4,4-BIPHENYLALANINE is also used in the preparation of (-)-Bestatin-based inhibitors. Bestatin, a naturally occurring aminoglycoside antibiotic, has been found to possess antitumor and immunomodulatory properties. The development of (-)-Bestatin-based inhibitors using BOC-D-4,4-BIPHENYLALANINE can lead to the creation of more potent and selective therapeutic agents for cancer treatment.