147983-33-3

Upstream product

• 145588-98-3 (4S)-4-isopropyl-3-(1-oxoheptyl)-2-oxazolidinone 
• 147983-31-1 tert-butyl (3S)-1-benzyloxycarbonyl-2-<(2R)-1-oxo-2-<(2,2,2-trichloroethoxycarbonyl)methyl>heptyl>hexahydropyridazine-3-carboxylate 
• 153427-71-5 2,2,2-Trichloroethyl 3-(R)-benzyloxycarbonyloctanoate 
• 147961-55-5 (4S)-4-isopropyl-3-<(2R)-2-(tert-butyloxycarbonylmethyl)-1-oxoheptyl>-2-oxazolidinone 
• 147961-56-6 tert-butyl (3R)-3-benzyloxycarbonyloctanoate 
• 153427-70-4 (3R)-3-benzyloxycarbonyloctanoic acid 
• 147961-57-7 (2R)-2-<(2,2,2-trichloroethoxycarbonyl)methyl>heptanoic acid 
• 2687-43-6 O-benzylhydoxylamine hydrochloride 
• 147961-58-8 tert-butyl (3S)-1-benzyloxycarbonyl-2-<(2R)-2-carboxymethyl-1-oxoheptyl>hexahydropyridazine-3-carboxylate 

Downstream Products

• 153744-13-9 N-<(1R)-1-<(1R)-1-methylpropyl>-2-oxobutyl>-(3S)-1-benzyloxycarbonyl-2-<(2R)-2-benzyloxyaminocarbonylmethyl-1-oxoheptyl>hexahydropyridazine-3-carboxamide 
• 147961-59-9 N-<(1S)-1-<(1S)-1-methylpropyl>-2-oxobutyl>-(3S)-1-benzyloxycarbonyl-2-<(2R)-2-benzyloxyaminocarbonylmethyl-1-oxoheptyl>hexahydropyridazine-3-carboxamide 
• 147983-32-2 (3S)-1-benzyloxycarbonyl-2-<(2R)-2-benzyloxyaminocarbonylmethyl-1-oxoheptyl>hexahydropyridazine-3-carboxylic acid 

Relevant academic research and scientific papers

Matlystatins, new inhibitors of type IV collagenases from Actinomadura atramentaria. IV. Synthesis and structure-activity relationships of matlystatin B and its stereoisomers

The first total synthesis of matlystatin B (1a), a low molecular weight inhibitor of type IV collagenases, was accomplished, and its absolute configuration was unambiguously determined. Furthermore, ten stereoisomers of 1a were synthesized, and the inhibi

Synthesis and determination of the absolute configuration of matlystatin B

The title compound (1) was first synthesized and its absolute configuration was determined as shown in figure 1.