147992-91-4

Upstream product

• 107-14-2 chloroacetonitrile 
• 147992-77-6 3-cyano-4-phenylmino-1,2-dihydropyridine-2-thione 
• 103607-75-6 2-chloro-3-cyano-4-anilinopyridine 
• 62-53-3 aniline 
• 836607-08-0 α-cyano-β-phenylminocrotonamide 
• 92119-57-8 α-cyano-β-dimethylaminocrotonamide 

Downstream Products

• 147992-82-3 3-Amino-4-phenylamino-thieno[2,3-b]pyridine-2-carbonitrile 

Relevant academic research and scientific papers

Synthesis and hydrolytic cleavage of 1-aryl-5-cyano-6-(2- dimethylaminovinyl)-4-oxo(thioxo)-1,4-dihydropyrimidines

1-Aryl-5-cyano-6-(2-dimethylaminovinyl)-4-oxo-1,4-dihydropyrimidines and their 4-thioxo analogs, which were prepared in three steps from cyanoacetamide and cyanothioacetamide, respectively, were subjected to hydrolysis. In aqueous AcOH, hydrolysis of N-(dimethylaminomethylene)-2-cyano-5-dimethylamino-2,4- pentadieneamide derivatives containing amino groups at position 3 afforded formylpyridones. The reaction of 2-cyano-3-dimethylaminothiocrotonamide with DMF dimethyl acetal gave rise to 3-cyano-4-dimethylamino-2-methylthiopyridine.