148-70-9 Usage
General Description
1-(2-ethoxyphenyl)urea, also known as EUP, is a chemical compound with the molecular formula C9H12N2O2. It is an organic compound that belongs to the class of ureas, which are derivatives of urea in which one or more hydrogen atoms are replaced by organic groups. EUP is a white to off-white solid at room temperature and is slightly soluble in water. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Additionally, EUP has been found to exhibit antifungal and herbicidal properties, making it an important compound in the development of agricultural and medicinal products. Studies have also shown that EUP may have potential applications in the treatment of certain diseases and disorders, further highlighting its significance in the field of organic chemistry and biochemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 148-70-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,4 and 8 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 148-70:
(5*1)+(4*4)+(3*8)+(2*7)+(1*0)=59
59 % 10 = 9
So 148-70-9 is a valid CAS Registry Number.
148-70-9Relevant academic research and scientific papers
A Straightforward Synthesis of N-Substituted Ureas from Primary Amides
Franck, Xavier,Glachet, Thomas,Ibert, Quentin,Lohier, Jean-Fran?ois,Reboul, Vincent,Saraiva Rosa, Nathalie
, p. 2099 - 2105 (2020/07/13)
A direct and convenient method for the preparation of N-substituted ureas is achieved by treating primary amides with phenyliodine diacetate (PIDA) in the presence of an ammonia source (NH 3 or ammonium carbamate) in MeOH. The use of 2,2,2-trifluoroethanol (TFE) as the solvent increases the electrophilicity of the hypervalent iodine species and allows the synthesis of electron-poor carboxamides. This transformation involves a nucleophilic addition of ammonia on the isocyanate intermediate generated in situ by a Hofmann rearrangement of the starting amide.
