148-90-3

Usage

Uses

Used in Chemical Synthesis:
4-(diethylamino)benzenediazonium chloride is used as a synthetic intermediate for the production of various organic compounds and dyes. Its reactivity and stability make it a valuable component in the synthesis of a wide range of chemical products.
Used in Photochemical Reactions:
In the field of photochemistry, 4-(diethylamino)benzenediazonium chloride is utilized as a photosensitive compound. Its ability to undergo reactions upon exposure to UV radiation allows it to be employed in various photochemical processes, such as the synthesis of photoresists and other light-sensitive materials.
Used in Allergen Research:
Due to its allergenic properties, 4-(diethylamino)benzenediazonium chloride is used as a research tool in the study of allergies and allergic reactions. It helps scientists understand the mechanisms behind allergic responses and develop potential treatments or preventive measures for those who are sensitive to 4-(diethylamino)benzenediazonium chloride.
Used in Safety and Environmental Applications:
4-(diethylamino)benzenediazonium chloride is also used in the development of safety protocols and environmental regulations. Its allergenic nature and inactivation by UV radiation make it an important factor to consider when designing safety measures for workplaces that use diazo copy paper or when establishing guidelines for the disposal and handling of such materials.

Contact allergens

It is a well-known allergen in diazo copy paper. This product is allergenic until exposed to light and inactivated by UV radiations.

InChI:InChI=1/C10H14N3/c1-3-13(4-2)10-7-5-9(12-11)6-8-10/h5-8H,3-4H2,1-2H3/q+1

Upstream product

• 2198-58-5 N,N-diethyl-1,4-phenylenediamine dihydrochloride 
• 91-66-7 N,N-diethylaniline 
• 93-05-0 N,N-diethylaniline 

Downstream Products

• 79573-60-7 4-(4-Diethylamino-phenylazo)-3-hydroxy-5-nitro-naphthalene-2-carboxylic acid 
• 79573-62-9 4-(4-Diethylamino-phenylazo)-3-hydroxy-5-nitro-naphthalene-2-carboxylic acid (4-methoxy-phenyl)-amide 
• 121501-64-2 7-chloro-2-(p-diethylaminophenyl)-2H-benzotriazolyl-5-amine 
• 121501-63-1 2-[4-(diethylamino)phenyl]-2H-benzotriazol-5-amine 

Relevant academic research and scientific papers

Preparation method of cationic blue dye

The invention belongs to the technical field of dyes, and particularly relates to a preparation method of a cationic blue dye. According to the invention, a compound II is used as a diazonium component and a compound I is used as a coupling component for synthesizing the cationic blue dye for the first time; and the method has the advantages of simple process, environmental friendliness, high product purity, high yield and the like. The results of multiple production experiments with scales not below pilot tests show that mother liquor (such as mother liquor in steps 2, 3 and 4) in the reaction process can be cyclically used 6-8 times without treatment, so the amount of high-salt, high-COD and high-chroma wastewater is greatly reduced, a working environment is effectively improved while product yield is further increased and reaction reagent cost is saved, and the product still keeps high purity; and thus, product quality is guaranteed, production cost is reduced, and obvious economicbenefits, social benefits and environmental benefits are produced.

APPLICATION OF FLUORESCENT TRIAZOLES TO ANALYTICAL CHEMISTRY. IV. DEVELOPMENT OF A NEW FLUORESCENT PROBE FOR BASIC DRUG-α1-ACID GLYCOPROTEIN BINDING MEASUREMENT

A fluorescent probe applicable to protein binding measurement was developed.Several 2-phenylbenzotriazolyl-5-amine derivatives having an amino group on the 2-phenyl ring were synthesized.Their fluorescence characteristics and the binding affinity to α1-acid glycoprotein (α1-AGP) were investigated.They were practically non-fluorescent in aqueous solution, but were highly fluorescent in the presence of α1-AGP.This fluorescence was due to the binding of these compounds to α1-AGP.Of all the compounds synthesized, 7-chloro-2-(p-diethylaminophenyl)-2H-benzotriazolyl-5-amine (CDBA) bound to α1-AGP most strongly and was used as a fluorescent probe.The binding parameters of CDBA were estimated by the fluormetric titration method to be log K = 6.18 and n = 0.40.The fluorescence of CDBA in the α1-AGP solution was markedly quenched in the presence of basic drugs, indicating that these drugs competitively displace CDBA bound to α1-AGP.The binding constants of the basic drugs were calculated, based on the decrease of fluorescence intensity in the presence of the drug.The binding strength of the drugs tested ranged from 4.7 to 6.8 as log K value.Keywords: fluorescent probe; fluorescence characteristics; protein binding; binding parameter; α-acid glycoprotein; competition; basic drug; benzotriazole: 7-chloro-2-(p-diethylaminophenyl)-2H-benzotriazolyl-5-amine