121501-63-1

Basic information

• Product Name: 2-[4-(diethylamino)phenyl]-2H-benzotriazol-5-amine
• Synonyms: 2-[4-(diethylamino)phenyl]-2H-benzotriazol-5-amine
• CAS NO: 121501-63-1
• Molecular Weight: 281.36
• Mol File: 121501-63-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-[4-(diethylamino)phenyl]-2H-benzotriazol-5-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(diethylamino)phenyl]-2H-benzotriazol-5-amine(121501-63-1)
• EPA Substance Registry System: 2-[4-(diethylamino)phenyl]-2H-benzotriazol-5-amine(121501-63-1)

Safety Data

• Hazardous Substances Data: 121501-63-1(Hazardous Substances Data)

Upstream product

• 148-90-3 4-diethylamino-benzenediazonium; chloride 
• 108-45-2 m-phenylenediamine 
• 93-05-0 N,N-diethylaniline 
• 2198-58-5 N,N-diethyl-1,4-phenylenediamine dihydrochloride 
• 541-69-5 m-phenylenediamine dihydrochloride 

Relevant articles and documents

Reactivity-based detection of copper(II) ion in water: Oxidative cyclization of azoaromatics as fluorescence turn-on signaling mechanism

An oxidative cyclization reaction transforms nonemissive azoanilines into highly fluorescent benzotriazoles. We have found that introduction of multiple electron-donating amino groups onto a simple o-(phenylazo)aniline platform dramatically accelerates its conversion to the emissive polycyclic product. Notably, this chemistry can be effected by μM-level concentrations of copper(II) ion in water (pH = 6-8) at room temperature to elicit >80-fold enhancement in the green emission at λem = 530 nm. Comparative kinetic and electrochemical studies on a series of structural analogues have established that the accelerated reaction rates correlate directly with a systematic cathodic shift in the oxidation onset potential of the azo precursors. In addition, single-crystal X-ray crystallographic analysis on the most reactive derivative revealed the presence of a five-membered ring intramolecular hydrogen-bonding network. An enhanced contribution of the quinoid-type resonance in such conformation apparently facilitates the mechanistically required proton transfer step, which, in conjunction with electron transfer at lower oxidation potential, contributes to a rapid cyclization reaction triggered by copper(II) ion in water.

TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY

There are disclosed compound of Formula (I) or (II) wherein A1, A2, A3, A4and A5, which may be the same or different, represent N or CR1, R9 represents - L -R3, in whi