1480-66-6 Usage
General Description
6-chloro-2-(trifluoromethyl)pyrimidin-4-amine is a chemical compound with the molecular formula C5H3ClF3N3. It is a pyrimidine derivative with a chlorine atom at the 6th position and a trifluoromethyl group at the 2nd position of the pyrimidine ring. 6-chloro-2-(trifluoromethyl)pyrimidin-4-amine is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is known for its versatile reactivity and is often employed as a building block in the production of various bioactive molecules. Its properties and applications make it a valuable compound in the field of medicinal chemistry and organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 1480-66-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,8 and 0 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1480-66:
(6*1)+(5*4)+(4*8)+(3*0)+(2*6)+(1*6)=76
76 % 10 = 6
So 1480-66-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H3ClF3N3/c6-2-1-3(10)12-4(11-2)5(7,8)9/h1H,(H2,10,11,12)
1480-66-6Relevant articles and documents
PqsR INVERSE AGONISTS
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Page/Page column 50; 51, (2020/01/31)
The present invention relates to a compound according to general formula (I), which acts as an inhibitor of PqsR (the currently only known receptor for the Pseudomonas Quinolone Signal (PQS)); to a pharmaceutical composition containing one or more of the compound(s) of the invention; to a combination preparation containing at least one compound of the invention and at least one further active pharmaceutical ingredient; and to uses of said compound(s), including the use as a medicament, e.g. the use in the treatment or prophylaxis of a bacterial infection, especially a Pseudomonas aeruginosa or Burkholderia infection.