148014-93-1

Basic information

• Product Name: 5-chloro-1-(1-methylethyl)-2-(4-methylpiperazin-1-yl)-1H-benzimidazol-6-amine
• CAS NO: 148014-93-1
• Molecular Formula: C₁₅H₂₂ClN₅
• Molecular Weight: 307.8217
• Mol File: 148014-93-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 464.9°C at 760 mmHg
• Flash Point: 235°C
• Density: 1.34g/cm³
• Vapor Pressure: 8.03E-09mmHg at 25°C
• Refractive Index: 1.663
• CAS DataBase Reference: 5-chloro-1-(1-methylethyl)-2-(4-methylpiperazin-1-yl)-1H-benzimidazol-6-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-1-(1-methylethyl)-2-(4-methylpiperazin-1-yl)-1H-benzimidazol-6-amine(148014-93-1)
• EPA Substance Registry System: 5-chloro-1-(1-methylethyl)-2-(4-methylpiperazin-1-yl)-1H-benzimidazol-6-amine(148014-93-1)

Safety Data

• Hazardous Substances Data: 148014-93-1(Hazardous Substances Data)

Upstream product

• 148014-96-4 5-chloro-1-isopropyl-2-(4-methyl-1-piperazinyl)-6-nitrobenzimidazole 
• 7440-66-6 zinc 
• 89-61-2 2,5-dichloronitrobenzene 
• 148014-95-3 5-chloro-1-isopropyl-2-(4-methyl-1-piperazinyl)benzimidazole 
• 148014-94-2 2,5-dichloro-1-isopropylbenzimidazole 
• 89659-68-7 5-chloro-2-<(1-methylethyl)amino>aniline 
• 89659-82-5 5-chloro-1,3-dihydro-1-(1-methylethyl)-2H-benzimidazol-2-one 
• 89659-66-5 4-chloro-N-isopropyl-2-nitrobenzenamine 
• 109-01-3 1-methyl-piperazine 

Relevant articles and documents

Benzimidazole derivative, process for preparing the same, antiemetic agent containing the same as active ingredient and intermediate compound for preparing the same

A benzimidazole derivative having the following formula (I): STR1 or a pharmaceutically acceptable acid addition salt thereof, a process for preparing the same, an antiemetic agent containing the same as an active ingredient and an intermediate compound for preparing the same. The above novel benzimidazole derivative has a continuous 5-HT3 antagonistic activity, shows preventive and therapeutic effects against vomiting caused by cisplatin and has a low toxicity, and hence, is useful as an antiemetic agent against vomiting due to chemotherapeutic treatment with cisplatin etc.