1480331-85-8

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 115076-24-9 1-cyano-3, 4-dimethylphosphole 

Downstream Products

• 86153-21-1 4-Methoxy-phenyldibromphosphan 
• 1480332-04-4 C₁₅H₂₇N₂OPS 
• 311820-22-1 Bis(diethylamino)(4-methoxyphenyl)phospine 

Relevant academic research and scientific papers

An unconventional synthesis of dibromophosphines

Dibromophosphines, RPBr2, are obtained by reaction of tetrabromomethane with 7-substituted 7-phosphanorbornenes in toluene at ca. 100 °C. The phosphanorbornenes are obtained in situ by cycloaddition of N-phenylmaleimide with 1-substituted 3,4-d

FeCl2Catalyzed Three-Component Reactions of Phospholes, Pyrrolidine, and Ketones (Aldehydes): Chemoselective Synthesis of 1-Phosphafulvenes

We have developed an unprecedented approach for the synthesis of transient 1-phosphafulvenes through three component reactions of phospholes. The generation of 1-phosphafulvenes was demonstrated by in situ [6 + 4] cycloaddition with 2H-phospholes and [6 + 6] self-dimerization. The [6 + 4] and [6 + 6] reaction pathway could be modulated by the starting ketones and aldehydes. The construction of 1-phosphafulvenes is illustrated by a proposed mechanism combining nucleophilic addition of phospholide to the iminium or isomerized azomethine ylide and a [1,5]-shift of phosphole.