1480740-77-9

Upstream product

• 90-96-0 bis(p-methoxyphenyl)methanone 
• 3988-03-2 bis(4-bromophenyl)methanone 

Downstream Products

• 2165348-28-5 4,4'-[2,2-bis(4-methoxyphenyl)vinylidene]bisbenzaldehyde 
• 2029185-29-1 4,4’-(2,2-bis(4-bromophenyl)ethene-1,1-diyl)diphenol 

Relevant academic research and scientific papers

Aggregation induction of tetraphenylethylene AIEgen and its supramolecular aggregates toward light-emitting diodes

Aggregation behavior of luminophores is a subject of great interest over more than half a century. Aggregation generally causes quenching of luminescence of luminophores, which is detrimental for the solid state electroluminescence device fabrication. In

Identification of the donor-substitution effect of tetraphenylethylene AIEgen: Synthesis, photophysical property analysis, and bioimaging applications

Various aggregation-induced emission luminogen (AIEgen) derivatives based on TPE (tetraphenylethylene) containing the electron-donating moiety (–NMe2, –OMe) and bromine (–Br) moiety were prepared, which are key intermediates for tuning the emis

Antibacterial organic compound as well as preparation method and application thereof

The invention relates to the technical field of antibacterial agents, and particularly discloses an antibacterial organic compound as well as a preparation method and application thereof. The structural formula of the antibacterial organic compound is as

Sensing array with mitochondrial targeting and aggregation-induced emission effects and application of sensing array in cell discrimination

The invention relates to a sensing array capable of distinguishing cells. The sensing array provided by the invention comprises five tetraphenyl ethylene derivatives with mitochondrial targeting and aggregation-induced emission effects. According to the tetraphenyl ethylene derivatives disclosed by the invention, a molecular probe D-A structure is adjusted by adjusting donor-acceptor groups and different cationic groups, so that different fluorescence spectrum properties are realized, and different electrostatic and hydrophobic interactions with cells are realized; the synthesis is easy; goodbiocompatibility and light stability are realized; cell mitochondria can be effectively targeted for cell imaging; different probes and different cells generate differential fluorescence response; byanalyzing different fluorescence responses, different cancer cells can be discriminated and cell types can be predicted. A new method for early cancer detection is designed and has potential application in the aspect of cancer cell clinical examination.

Strategies to Enhance the Photosensitization: Polymerization and the Donor–Acceptor Even–Odd Effect

A particular challenge in the design of organic photosensitizers (PSs) with donor–acceptor (D-A) structures is that it is based on trial and error rather than specific rules. Now these challenges are addressed by proposing two efficient strategies to enhance the photosensitization efficiency: polymerization-facilitated photosensitization and the D-A even–odd effect. Conjugated polymers have been found to exhibit a higher 1O2 generation efficiency than their small molecular counterparts. Furthermore, PSs with A-D-A structures show enhanced photosensitization efficiency over those with D-A-D structures. Theoretical calculations suggest an enhanced intersystem crossing (ISC) efficiency by these strategies. Both in vitro and in vivo experiments demonstrate that the resulting materials can be used as photosensitizers in image-guided photodynamic anticancer therapy. These guidelines are applicable to other polymers and small molecules to lead to the development of new PSs.

Diarylethene fluorescent molecular switch and preparation method and application thereof

The invention discloses an aggregation-induced emission type diarylethene fluorescent molecular switch and a preparation method and application thereof. The aggregation-induced emission type diarylethene fluorescent molecular switch is characterized in that an AIE radical is introduced to gain solid or aggregation strong emission capacity; two diarylethene can be used for quickly quenching fluorescence of fluorescent radicals which aggregate in the surrounding under the irradiation of ultraviolet rays or visible light, thus achieving the purpose of high fluorescent switch ratio. According to the light control type AIE-effect fluorescent molecular switch, the limitation that traditional fluorescent chromophore leads to fluorescence quenching is broken; in addition, the fluorescent molecularswitch in solid and aggregation state has the advantages of being high in switch ratio and high in fluorescence quenching efficiency by being compared with the fluorescent molecular switch in solution state; the fluorescent molecular switch is applicable to information storage under solid state and photoelectric devices and has potential application in biosensing and fluorescence imaging.

Tetraphenylethylene indole derivative, preparation method therefor and application of tetraphenylethylene indole derivative in cell imaging and thiol compound analysis

The invention provides a tetraphenylethylene indole derivative molecule, a preparation method therefor and an application of the tetraphenylethylene indole derivative molecule in the fields of cell imaging and detection of thiols in cells. According to the application, two indole salt structures are introduced to a tetraphenyl ethylene molecule, and the molecule is applied to the cell imaging and thiol compound analysis as a fluorescence molecule probe by using fluorescence emission characteristics of the molecule. Due to the introduction of the two indole salt structures, the interaction between the molecule probe and the surface of a mitochondrion in a cell can be enhanced, then, the selective imaging of the mitochondrion and the detection of a membrane potential of the mitochondrion are achieved, and a more-sensitive potential indicating result is obtained. The induced luminescence integrated fluorescence molecule provided by the invention has the advantages of low cell toxicity and good luminescence stability, can be applied to the analysis of thiol compounds, the mitochondrion imaging of the cells and the detection of membrane potential changes of mitochondria and shows a potential application value in the field of biomedicines.

Synthesis of gem-tetraphenylethylene oligomers utilizing Suzuki reaction and their aggregation properties

Four new gem-tetraphenylethylene-based oligomers were synthesized by Suzuki coupling reaction in good yields (62-80%) and characterized by NMR, mass spectrometer and elemental analysis. The absorption maxima of the synthesized oligomers in the solution possess similar absorption bands located at 328-332 nm. They are shown to be thermally stable and emit light in blue region (404-485 nm). All the oligomers are AIE-active, emit weakly in solutions with Φf values not exceeding 4%, become strong emitters in the aggregated states and the PL intensity values increase up to 18-fold. The results of CV measurements of the oligomers showed good reversibility, indicating that the compounds have good electrochemical stability. The HOMO values of the oligomers are in the range of -5.63 to -5.61 eV. The photoluminescence properties in aggregate-state and the high HOMO energy levels of these oligomers make them applicable as an active material for a light-emitting device.