148083-39-0Relevant academic research and scientific papers
Structure and total Synthesis of sporol and neosporol
Ziegler, Fredrick E.,Metcalf III, Chester A.,Nangia, Ashwini,Schulte, Gayle
, p. 2581 - 2589 (1993)
The complete details of the synthesis of sporol (1) and its formerly assigned structure, neosporol (2), are provided. A highly stereoselective Claisen rearrangement sets the C5-C6 stereochemistry of the trichothecene skeleton. Subseq
THE SYNTHESIS OF NEOSPOROL: A TRICHOTHECENE IN SEARCH OF A NATURAL PRODUCT
Ziegler, Frederick E.,Nangia, Ashwini,Schulte, Gayle
, p. 1669 - 1672 (1988)
The synthesis of neosporol 14, a yet to be discovered trichothecene, is described.The critical reaction is a highly diastereoselective Claisen rearrangement that sets the C5-C6 stereochemistry.
ALDOSTERONE SYNTHASE INHIBITORS
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Page/Page column 65, (2016/06/28)
The present invention relates to compounds of the formulas (IA) and (IB) and pharmaceutically acceptable salts thereof, wherein A and R1 - R6, are as defined herein. The invention also relates to pharmaceutical compositions comprisin
