148117-67-3Relevant academic research and scientific papers
A highly diastereoselective aldol reaction of dicobalt hexacarbonyl propynal complex and uncomplexed propynal: A stereoselective divergent synthesis of (±)-PS-5 and (±)-6-Epi-PS-5
Mukai,Kataoka,Hanaoka
, p. 7553 - 7556 (1991)
The aldol reaction of cobalt complexed propynal 1 with O-silyl ketene O,S-acetals 3 gave the syn-products exclusively, while the uncomplexed propynal 2, the corresponding anti-compounds. A successful application of these stereoselective reactions to a syn
Highly Diastereoselective Aldol Reactions of Cobalt-complexed and Uncomplexed Propynals with O-Silyl Ketene O,S-Ketals: Highly Stereoselective Divergent Formal Syntheses of the β-Lactam Antibiotics (+/-)-PS-5 and (+/-)-epi-PS-5
Mukai, Chisato,Kataoka, Osamu,Hanaoka, Miyoji
, p. 563 - 572 (2007/10/02)
Treatment of a cobalt-complexed propynal derived from 3-trimethylsilylprop-2-ynal with O-silyl ketene O,S-ketals afforded the syn-aldol products exclusively, whereas the uncomplexed substrate 3-trimethylsilylprop-2-ynal provided the anti-ones exclusively
