14812-19-2

Usage

Uses

Used in Organic Synthesis:
12-Chloro-12-oxododecanoic acid ethyl ester is used as a synthetic intermediate for the production of various organic compounds. Its chemical structure allows it to be a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 12-Chloro-12-oxododecanoic acid ethyl ester is used as a key component in the development of new drugs. Its unique properties make it a valuable asset in the synthesis of novel therapeutic agents, potentially contributing to the treatment of various diseases and medical conditions.
Used in Agrochemical Industry:
12-Chloro-12-oxododecanoic acid ethyl ester is also utilized in the agrochemical industry for the synthesis of new pesticides and other crop protection agents. Its incorporation into these products can enhance their effectiveness and selectivity, leading to improved agricultural yields and more sustainable farming practices.
Used in Specialty Chemicals:
In the specialty chemicals sector, 12-Chloro-12-oxododecanoic acid ethyl ester is employed as a raw material for the production of various high-value chemicals. These can include additives for the plastics and polymer industry, as well as components for the formulation of advanced materials with specific properties and applications.

Upstream product

• 66003-63-2 1,12-dodecadicarboxylic acid monoethyl ester 
• 693-23-2 1,12-dodecanedioic acid 
• 64-17-5 ethanol 
• 4834-98-4 1,12-dodecanedioyl dichloride 
• 505-95-3 12-hydroxydodecanoic acid 
• 78640-13-8 12-hydroxydodecanoic acid ethyl ester 

Downstream Products

• 106-14-9 12-Hydroxystearic acid 
• 74815-67-1 ethyl 12-hydroxystearate 
• 1292292-53-5 C₃₄H₆₄NO₈⁽¹⁺⁾*I^(1-) 
• 821773-43-7 C₄₇H₆₆N₆O₁₁S₃ 
• 1394010-75-3 C₃₆H₄₈N₄O₇S₃ 

Relevant academic research and scientific papers

Functionalised nanoparticles, their production and use

Stable complexes are described, formed by mono- and di-functional compounds bound to nanoparticles composed of various types of transition metal oxides and of metals useful in the production processes of different types of new materials (such as for examp

Synthesis, characterization, and in vitro transfection activity of charge-reversal amphiphiles for DNA delivery

A series of charge-reversal lipids were synthesized that possess varying chain lengths and end functionalities. These lipids were designed to bind and then release DNA based on a change in electrostatic interaction with DNA. Specifically, a cleavable ester linkage is located at the ends of the hydrocarbon chains. The DNA release from the amphiphile was tuned by altering the length and position of the ester linkage in the hydrophobic chains of the lipids through the preparation of five new amphiphiles. The amphiphiles and corresponding lipoplexes were characterized by DSC, TEM, and X-ray, as well as evaluated for DNA binding and DNA transfection. For one specific charge-reversal lipid, stable lipoplexes of approximately 550 nm were formed, and with this amphiphile, effective in vitro DNA transfection activities was observed.

Chain-Substituted Lipids in Monolayer Films. A Study of Molecular Packing

A series of highly purified fatty acids and phospholipids, each possessing a chain substituent of varying size (methyl, n-butyl, or phenyl) at varying locations (carbon 4, 8, 12, or 16 of an 18-carbon chain) were synthesized.Pressure-area isotherms, obtained with the aid of a film balance, revealed how these molecules, either individually or admixed, pack in monomolecular films.Two examples will illustrate here the type of information secured by the method. (a) The presence of a methyl at carbon 16 of a single phospholipid chain has a negligible effect on the molecular packing within a "liquid" film.A methyl on carbon 16 of both chains, on the other hand, is highly expansive.Even a single methyl at position 8 perturbs the film packing appreciably, thus indicating less available space near the center of the chain. (b) Deviation from ideality in mixed fatty acid films can be explained by interdigitation that reduces steric repulsion among the substituents.It is also possible to observe by means of film balance techniques the extrusion of 8-butylstearic acid when it contaminates a film composed largely of stearic acid.Approximate SHADOW calculations could, in many cases, provide film areas in reasonable agreement with experiment.

SYNTHESIS OF 12-HYDROXYCARBOXYLIC ACIDS FROM 11-CYANOUNDECANOIC ACID

The synthesis of 12-hydroxy carboxylic acids with the general formula CH3(CH2)n.CHOH.(CH2)10COOH, where n = 1, 3, 5, and 7, was realized from 11-cyanoundecanoic acid and organoaluminium compounds.