148192-24-9

Upstream product

• 60633-78-5 2-(2-bromoethoxy)benzaldehyde 
• 157432-87-6 5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene 
• 89-95-2 2-methyl-benzyl alcohol 
• 90-02-8 salicylaldehyde 

Downstream Products

• 506444-43-5 C₆₂H₇₄Cl₂O₆ 
• 1094524-41-0 C₇₆H₈₄N₄O₈ 
• 1094597-60-0 C₇₈H₈₈N₄O₁₀ 
• 1094524-30-7 C₆₂H₇₆N₄O₆ 
• 506444-42-4 C₆₂H₇₆O₈ 

Relevant academic research and scientific papers

Synthesis of the tripodal-amine capped benzo crown p-tert-butylcalix[4]arene and its host-guest chemistry

The tripodal-amine capped benzo crown p-tert-butylcalix[4]arene (6) was synthesised. The basicity of the nitrogen donors in 6 based on the protonation constants was measured by potentiometric titration. The complexation studies of 6 with Zn(II) ions were

An organic-inorganic nanohybrid of a calix[4]arene based chromogenic chemosensor for simultaneous estimation of ADP and NADH

The versatility in the environmental and biological applications of nanohybrids encouraged us to prepare a novel chemosensor based on an organic-inorganic nanohybrid (H1) employing receptor 1 (R1), which was synthesized via the Schiff's base condensation reaction of a calix[4]arene derivative and an aliphatic amine. Techniques such as DLS and TEM were employed for the characterization of organic nanoparticles (N1) and H1. Further, sensor properties of H1 were explored towards various biologically important molecules in aqueous media using UV-visible spectroscopy. The proposed sensor responded effectively for the selective and simultaneous nanomolar determination of adenosine diphosphate (ADP) and reduced nicotiniamide adenine dinucleotide (NADH). The response was not affected by the presence of each analyte or any other potentially interfering biomolecule or a high concentration of salt. The proposed sensor was also found to show a stable response in an extensive pH range thus widening its practical applicability. H1 was able to detect a minimum concentration (detection limit) of 6.11 × 10-9 M of ADP and 4.87 × 10-9 M of NADH. The prepared hybrid was subjected to real sample analysis for the determination of ADP and NADH in samples prepared artificially by adding known concentrations of NADH and ADP in solution and also in a mixture of both.

Comparative study of azobenzene and stilbene bridged crown ether p-tert-butylcalix[4]arene

Photo-switchable calixarenes consisting of a stilbene or azobenzene bridge, spanning the narrow rim as a switching unit, were synthesized through reductive coupling of o-, m- and p-bis-benzaldehyde and bis-nitrobenzene-substituted calix[4]arenes. Both cis- and trans-stilbenes were produced from the reductive coupling of the o- and m-bis-benzaldehyde with the cis isomer being predominant for both regioisomers, whilst the coupling of p-bis-benzaldehyde gave only cis product. On the other hand, the only isolable product obtained from the reductive coupling of bis-o- and bis-m-nitrobenzene was the corresponding trans-azobenzene and the coupling product from bis-p-nitrobenzene was not stable. Each of the synthesized compounds showed a photostationary state in their cis-trans isomerization. The complexation of alkali metal ions was observed for only the o-azobenzene derivative suggesting that the lone pair of N-atom in the azo bridge participates in this process.

Synthesis of calix[4]crowns containing soft donor atoms and a study of their metal-cation binding properties: Highly selective receptors for Cu2+

Two new calix[4]arenethiacrown derivatives 1 and 2 in the cone conformation were synthesized by two different pathways in good yield. Their complexation properties toward alkali, alkaline earth and transition metal cations were studied in acetonitrile at 298.15 K using a conductometric titration technique. The selectivity for Cu2+ over other cations with these novel ligands was excellent.

Synthesis of new Schiff base p-tert-butyl-calix[4]arene with imine units spanning 1,3-distal positions on the lower rim

A new Schiff base p-tert-butylcalix[4]arene with imine units has been synthesized in good yield by simple [1+1] simple condensation.

Synthesis of tripodal aza crown ether calix[4]arenes and their supramolecular chemistry with transition-, alkali metal ions and anions

Tripodal aza crown ether calix[4]arenes, 5a, 5b, 6a and 6b, have been synthesized. The structure of protonated 5a was elucidated by X-ray crystallography to be a self-threaded rotaxane. Complexation studies of 5a and 5b towards anions using Na+

Aza crown ether calix[4]arenes containing cation and anion binding sites: Effects of metal ions towards anion binding ability

Tripodal aza crown ether calix[4]arenes containing both cation and anion binding sites (5a and 5b) have been synthesized. The X-ray analysis shows that 5a forms a self-threaded rotaxane-like structure in the solid state. 1H NMR titrations of the two ligands with various halide anions indicate that 5a and 5b can form complexes with Br- and I- but not F-. However, both compounds form more stable complexes with I- than with Br- in the presence of Bu4N+. The presence of K+ enhances the binding ability of 5a towards Br-.