1482520-24-0

Basic information

• Product Name: 1-[1-phenyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]pent-4-en-2-ol
• Synonyms: 1-[1-phenyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]pent-4-en-2-ol
• CAS NO: 1482520-24-0
• Molecular Weight: 296.292
• Mol File: 1482520-24-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[1-phenyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]pent-4-en-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[1-phenyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]pent-4-en-2-ol(1482520-24-0)
• EPA Substance Registry System: 1-[1-phenyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]pent-4-en-2-ol(1482520-24-0)

Safety Data

• Hazardous Substances Data: 1482520-24-0(Hazardous Substances Data)

Upstream product

• 1482520-12-6 3-(2,2-dimethoxyethyl)-5-trifluoromethyl-1H-1-phenylpyrazole 
• 100-63-0 phenylhydrazine 
• 1140485-84-2 4,6,6-trimethoxy-1,1,1-trifluorohex-3-en-2-one 
• 1482520-21-7 2-[1-phenyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]acetaldehyde 
• 106-95-6 allyl bromide 

Relevant articles and documents

Easy and regioselective access to dimethyl acetal-protected heterocycles and their efficient allylation reactions mediated by allylaluminum reagent

This paper describes easy access to twelve examples of five- and six-membered heterocycles (monocyclic and fused) containing a dimethyl acetal aldehyde function and/or a trifluoromethyl substituent, in good to excellent yields (72-98%). The dimethyl acetal-protected heterocycles were obtained in one-step via regioselective cyclocondensation reactions of 4,6,6-trimethoxy-1,1, 1-trifluorohex-3-en-2-one with 1,2-, 1,3- and 1,5-dinucleophiles (hydrazines, hydrazides, hydroxylamine, 1-acetylguanidine and 1,8-diaminonaphthalene). Subsequently, to demonstrate a potential synthetic application, some pyrazole rings containing dimethyl acetal moiety were converted to the respective secondary homoallylic alcohols by efficient allylation reactions employing allylaluminum reagent in 84 to 90% yields.