148260-64-4Relevant academic research and scientific papers
Probing the mycobacterial trehalome with bioorthogonal chemistry
Swarts, Benjamin M.,Jewett, John C.,Fox, Douglas M.,Siegrist, M. Sloan,Bertozzi, Carolyn R.,Holsclaw, Cynthia M.,Leary, Julie A.,Alber, Marina,Kalscheuer, Rainer
supporting information, p. 16123 - 16126,4 (2020/09/09)
Mycobacteria, including the pathogen Mycobacterium tuberculosis, use the non-mammalian disaccharide trehalose as a precursor for essential cell-wall glycolipids and other metabolites. Here we describe a strategy for exploiting trehalose metabolic pathways
An improved synthesis of 4-azido-4-deoxy- and 4-amino-4-deoxy-α,α-trehalose and their epimers
Bassily, Rafik W.,El-Sokkary, Ramadan I.,Silwanis, Basim Azmy,Nematalla, Asaad S.,Nashed, Mina A.
, p. 197 - 208 (2007/10/02)
The order of esterification of the eight hydroxyl groups of α,α-trehalose is HO-6,6' > HO-2,2' > HO-3,3' > HO-4,4'.Under the appropriate conditions of benzoylation, the heptabenzoate with HO-4' free was obtained in good yield (58percent), along with the o
