61207-38-3

Upstream product

• 99-20-7 TREHALOSE 
• 98-88-4 benzoyl chloride 

Downstream Products

• 148260-64-4 4-Azido-2,3,6-tri-O-benzoyl-4-deoxy-α-D-glucopyranosyl 2,3,4,6-tetra-O-benzoyl-α-D-glucopyranoside 
• 148180-46-5 2,3,6-Tri-O-benzoyl-4-deoxy-4-trifluoroacetamido-α-D-glucopyranosyl 2,3,4,6-tetra-O-benzoyl-α-D-glucopyranoside 
• 51855-99-3 4'-Amino-4'-deoxy-α-D-galactopyranosyl α-D-glucopyranoside 
• 51855-99-3 4-amino-4-deoxy-α-D-glucopyranosyl α-D-glucopyranoside 
• 148180-43-2 2,3,6-Tri-O-benzoyl-4'-O-trifluoromethylsulfonyl-α-D-glucopyranosyl 2,3,4,6-tetra-O-benzoyl-α-D-glucopyranoside 

Relevant academic research and scientific papers

Total Synthesis of Emmyguyacins A and B, Potential Fusion Inhibitors of Influenza Virus

Fungal glycolipids emmyguyacins A and B inhibit the pH-dependent conformational change of hemaglutinin A during replication of the Influenza virus. Herein, we report the first total synthesis and structure confirmation of emmyguyacins A and B. Our efficient route, which involves regioselective functionalization of trehalose, allows rapid access to adequate amounts of chemically pure emmyguyacin analogues including the desoxylate derivatives for SAR studies.

An improved synthesis of 4-azido-4-deoxy- and 4-amino-4-deoxy-α,α-trehalose and their epimers

The order of esterification of the eight hydroxyl groups of α,α-trehalose is HO-6,6' > HO-2,2' > HO-3,3' > HO-4,4'.Under the appropriate conditions of benzoylation, the heptabenzoate with HO-4' free was obtained in good yield (58percent), along with the o