148303-20-2Relevant articles and documents
Insecticidal Activity of Sesquilignans with a 3-Aryl-6-methoxy-2-methoxymethyl-1,4-benzodioxanyl Group
Yamauchi, Satoshi,Ishibashi, Fumito,Taniguchi, Eiji
, p. 1760 - 1768 (2007/10/02)
Five analogs of the insecticidal lignan of the Phryma were synthesized by modifying its 3,4-methylenedioxyphenyl group with a phenyl, 4-methoxyphenyl, 3-methoxyphenyl, 3,4-dimethoxyphenyl, or 4-chlorophenyl group to evaluate the contribution of the methylenedioxy function to the activity.The assay results revealed that the 4-oxymethylene part of the 3,4-methylenedioxyphenyl group collaborated more for strengthening the insecticidal activity than the 3-oxymethylene part did.Unexpectedly, the 3,4-dimethoxyphenyl analog was totally inactive, even at a high dose level.