148312-55-4 Usage
Description
Tert-Butyl thiazolidine-3-carboxylate is a synthetic chemical compound belonging to the thiazolidine family, characterized by a thiazolidine ring and a carboxylate group. It is known for its versatile reactivity and potential biological activity, making it a valuable building block in the synthesis of pharmaceuticals and agrochemicals. The tert-butyl group attached to the thiazolidine ring provides stability and steric hindrance, which is beneficial in the development of various organic compounds. However, it is crucial to handle this chemical with care and follow safety guidelines due to its potential hazards.
Uses
Used in Pharmaceutical Industry:
Tert-Butyl thiazolidine-3-carboxylate is used as a building block for the synthesis of various pharmaceuticals due to its versatile reactivity and potential biological activity. Its unique structure allows for the development of new drugs with improved efficacy and safety profiles.
Used in Agrochemical Industry:
In the agrochemical industry, Tert-Butyl thiazolidine-3-carboxylate is utilized as a key intermediate in the synthesis of agrochemicals, such as pesticides and herbicides. Its reactivity and stability contribute to the creation of effective and environmentally friendly products.
Used in Organic Chemistry Research:
Tert-Butyl thiazolidine-3-carboxylate is employed as a valuable molecule in organic chemistry research, where its unique structure and reactivity are explored for the development of novel organic compounds and reactions. Its steric hindrance and stability make it an attractive candidate for studying various chemical transformations and mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 148312-55-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,3,1 and 2 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 148312-55:
(8*1)+(7*4)+(6*8)+(5*3)+(4*1)+(3*2)+(2*5)+(1*5)=124
124 % 10 = 4
So 148312-55-4 is a valid CAS Registry Number.
148312-55-4Relevant articles and documents
Model syntheses of thiazolidine nucleoside analogues
Rassu,Rassu, Gloria,Zanardi,Zanardi, Franca,Cornia,Cornia, Mara,Casiraghi,Casiraghi, Giovanni
, p. 1113 - 1120 (1996)
The syntheses of racemic thiazolidinyl thymine and cytosine derivatives 6a and 6b, and 10a and 10b, prototypes of a novel family of heterosubstituted nucleosides, have been achieved from rhodanine (3) or thiazolidine (7) by a short sequence of steps. The key reaction involved efficient coupling of silylated thymine and cytosine to N-Boc-protected 4- and 5- acetoxythiazolidines, 5 and 9, assisted by tert-butyldimethylsilyl trifluoro- methanesulfonate.
Enantioselective reaction of α-lithiated thiazolidines as new chiral formyl anion equivalents
Wang, Libo,Nakamura, Shuichi,Ito, Yuji,Toru, Takeshi
, p. 3059 - 3072 (2007/10/03)
The reaction of lithiated N-Boc-thiazolidine and N-Boc-benzothiazolidine with benzophenone in the presence of (-)-sparteine afforded the products with up to 97% ee and 93% ee, respectively. The reaction with various aromatic and aliphatic aldehydes also afforded the products with high enantioselectivity and moderate diastereoselectivity. Each diastereomer could be converted to optically active diols. Consequently, lithiated N-Boc-thiazolidine and N-Boc-benzothiazolidine serve as chiral formyl anion equivalents. The reaction was confirmed to proceed through a dynamic thermodynamic resolution pathway.
