148312-89-4

Upstream product

• 148312-84-9 (E)-(4R,5S,6R)-4,5,6-Tris-benzyloxy-7,7-bis-ethylsulfanyl-hept-2-enoic acid methyl ester 
• 148312-85-0 (E)-(4R,5S,6R)-4,5,6-Tris-benzyloxy-7-oxo-hept-2-enoic acid methyl ester 
• 116384-32-8 2,3,4-tri-O-benzyl-D-xylo-pentodialdose 1,1-diethyl dithioacetal 
• 148312-88-3 ((2S,5S,6R,7R,8S,8aS)-6,7,8-Tris-benzyloxy-2-hydroxy-3-oxo-octahydro-indolizin-5-yl)-acetic acid methyl ester 

Downstream Products

• 148312-90-7 ((2S,5S,6R,7R,8S,8aS)-6,7,8-Tris-benzyloxy-2-hydroxy-octahydro-indolizin-5-yl)-acetic acid 

Relevant academic research and scientific papers

Cycloaddition reactions of carbohydrate derivatives. Part IV. Synthesis of a tetrahydroxyindolizidine through a cyclic nitrone prepared from D-xylose

Intramolecular conjugate addition of the oxime from aldehyde 5 led to the formation of cyclic nitrone 6. 1,3-Dipolar cycloaddition of the latter with methyl acrylate gave the bicyclic 7 with high diastereoselection. Subsequent four-step transformation of