148367-35-5Relevant academic research and scientific papers
Magnesium mediated carbometallation of propargyl alcohols: Direct routes to furans and furanones
Forgione, Pat,Wilson, Peter D.,Fallis, Alex G.
, p. 17 - 20 (2000)
The addition of vinyl and aryl Grignard reagents to propargyl alcohols for the direct synthesis of furans and butenolides from a one pot reaction is described. These products arise from a putative magnesium chelate intermediate 2 upon reaction with various electrophiles. This chelate was also generated in situ from alkynyl lithium addition to aldehydes followed by magnesium exchange and Grignard addition. Thus, the complete substitution pattern for the furan ring may be controlled, as desired, through the judicious choice of substrates and reagents.
3,4-Disubstituted Furans, 5. Regiospecific Mono-ipso-Iodination of 3,4-Bis(trimethylsilyl)furan and Regiospecific ipso-Iodination of Trisboroxines to 4-Substituted 3-(Trimethylsilyl)furans and Unsymmetrical 3,4-Disubstituted
Song, Zhi Zhong,Wong, Henry N. C.
, p. 29 - 34 (2007/10/02)
4-Iodo-3-trimethylsilylfuran (2), obtained through the regiospecific iodination of 3,4-bis(trimethylsilyl)furan (1), underwent either palladium- or nickel-catalyzed cross-coupling reactions with terminal alkenes, terminal alkynes, areneboronic acids, bis(
Synthesis and Reactions of 3,4-Bis(trimethylsilyl)furan: Diels-Alder Cycloaddition, Friedel-Crafts Acylation, and Regiospecific Conversion to 3,4-Disubstituted Furans
Song, Zhi Zhong,Ho, Mei Sing,Wong, Henry N. C.
, p. 3917 - 3926 (2007/10/02)
As a versatile building block, 3,4-bis(trimethylsilyl)furan (1), conveniently obtained through a Diels-Alder reaction between 4-phenyloxazole and bis(trimethylsilyl)acetylene, was able to undergo Diels-Alder cycloadditions with dienophiles.In two separate
